Search results | J. Murrey Atkins Library

Title: A NOVEL ANTIBODY FOR THE DETECTION AND TREATMENT OF PANCREATIC DUCTAL ADENOCARCINOMA
Author: Wu, Shuta
Date Created: 2017
Subjects--Topical: Biology, Oncology
Description: Pancreatic ductal adenocarcinoma (PDA) remains the most aggressive cancer with a 5-year survival rate below 10%. Two of the major contributors to this dismal prognosis are late-stage diagnosis and limited treatment options. Common symptoms of PDA ...

Title: Analysis and Development of Targeting Strategies for Bacterial Sugars
Author: Erickson, Katelyn
Date Created: 2018
Subjects--Topical: Chemistry, Biochemistry
Description: Bacterial cell surface exopolysaccharides aid in protecting microbes from the defense mechanisms of the host, and differ substantially in structure between species. Exploiting these structural differences would be advantageous to target certain ty...

Title: Approaches for Power Grid Management and Ancillary Services with DC-AC Micro-grids Comprising of PV Farm and Hybrid Energy Storage System
Author: Joshi, Aniket
Date Created: 2021
Subjects--Topical: Electrical engineering
Description: The emergence of the concept of DC grids comes from the fact that there is an increasing number of power grid components that naturally operate with DC power. The combined trend of DC sources and loads in power grids is an important player in the ...

Title: Bis(bipyridyl)silicon(IV) compounds – synthesis, characterization, and catalytic properties.
Author: Maguylo, Christina
Date Created: 2015
Subjects--Topical: Chemistry, Chemistry, Inorganic
Description: A series of novel hexacoordinate bis-bipyridylsilicon(IV) complexes have been synthesized by reacting [Si(bipy)2I2]I2 with the appropriate alcohol or diol. Characterization was done and crystal structures have been obtained for the complexes: [Si(...

Title: Chemoenzymatic Preparation of Probes for in vitro and Cellular Elucidation of Complex Bacteria Polysaccharides
Author: Reid, Amanda
Date Created: 2021
Subjects--Topical: Microbiology, Biochemistry, Analytical chemistry
Description: Bacteria play a major role in our health and wellbeing. The microbe-host interaction is often mediated by sugar polymers at the cell surface. An incredibly diverse amount of glycan variation exists throughout these structures, which makes identifi...

Title: DESIGN, SYNTHESIS AND CHARACTERIZATION OF MULTIFUNCTIONAL REDOX-RESPONSIVE PORPHYRIN-BASED POLYSILSESQUIOXANE NANOMATERIALS FOR PHOTODYNAMIC THERAPY
Author: Vega, Daniel
Date Created: 2015
Subjects--Topical: Materials science, Chemistry, Nanotechnology
Description: Photodynamic Therapy (PDT) is a minimally invasive clinically approved cancertreatment that was first applied in the early 20th century. PDT is an attractive alternative when compared to chemotherapy and radiation therapy due to the lack of harmfu...

Title: Long-term study of changes in microbiota in a Cystic Fibrosis patient
Author: Stokell, Joshua
Date Created: 2013
Subjects--Topical: Biology, Microbiology
Description: Application of culture-independent techniques have revealed the presence of more types of bacteria than were previously thought, which led to the current description of Cystic Fibrosis (CF) being a polymicrobial disease. We know this polymicrobial...

Title: RANK-L expression in Staphylococcus aureus- induced osteomyelitis, therapeutic intervention using nanotechnology and use of UV-killed bacteria as an osteoconductive coating for biomaterials.
Author: Somayaji, Shankari
Date Created: 2009
Subjects--Topical: Microbiology
Description: Staphylococcus aureus is responsible for approximately 80% of all cases of human osteomyelitis. RANK-L is an essential signal produced by osteoblasts and is required for full osteoclastic differentiation. PGE₂ - induced bone resorption involves bo...

Title: SYNTHESIS, CHARACTERIZATION, AND APPLICATION OF SILICA-BASED NANOPARTICULATE PLATFORMS FOR THE DELIVERY OF PHOTOSENSITIZERS IN THE USE OF PHOTODYNAMIC THERAPY FOR CANCER TREATMENT
Author: Lyles, Zachary
Date Created: 2018
Subjects--Topical: Nanoscience
Description: Triple negative breast cancer (TNBC) is a subtype of breast cancer which lacks expressions of hormonal receptors (ER/PR/HER2) and other meaningful targets. TNBC is characterized by intra-tumoral heterogeneities, high proliferative activity, poor p...

Title: Synthesis and characterization of single-walled carbon nanotubes for use in water purification
Author: Johnson, Billy
Date Created: 2016
Subjects--Topical: Materials science, Nanoscience, Chemistry
Description: As human health concerns over disinfection byproducts (DBPs) in drinking water increase, so does the need to development new materials that remove them rapidly and at high-efficiency. Ion exchange (IEX) is an effective method for the removal of na...

Title: Synthesis, Characterization and Functionalization of Anti-Bisarene Scaffolds
Author: Franklin, Joseph
Date Created: 2017
Subjects--Topical: Chemistry
Description: Since the advent of rational organic synthesis, practitioners in the field have been refining their craft to target compounds of immense complexity. Synthetic methodologies discovered through these pursuits have provided a fertile ground to expand...

Title: Synthesis, Characterization, and Reactivity of Cross-Conjugated Frameworks
Author: Hamilton, Victoria
Date Created: 2018
Subjects--Topical: Chemistry, Chemistry, Organic
Description: ABSTRACTVICTORIA LEIGH HAMILTON. Synthesis, Characterization, and Reactivity of Cross-Conjugated Frameworks. (Under the direction of MARKUS ETZKORN)Molecules with cross-conjugated -systems possess unique structures and reactivity due to their dis...

Title: THE DEVELOPMENT OF NOVEL THERAPEUTICS IN PANCREATIC AND BREAST CANCERS: POTENTIAL ROLE OF MUC1
Author: Besmer, Dahlia
Date Created: 2013
Subjects--Topical: Biology
Description: Pancreatic ductal adenocarcinoma (PDA) is the 4th leading cause of cancer-related deaths in the US, and breast cancer (BC) contributes to ~40,000 deaths annually. The development of novel therapeutic agents for improving patient outcome is of para...

Title: THE ROLE OF MUC1 IN REGULATION AND PROGRESSION OF CANCER
Author: Sahraeimanouchehrabadi, Mahnaz
Date Created: 2011
Subjects--Topical: Immunology, Biology, Oncology
Description: MUC1 is a heavily glycosylated transmembrane glycoprotein which is overexpressed and aberrantly glycosylated in most human carcinomas. MUC1 contains a large tandem repeat, a short transmembrane, and a small cytoplasmic tail. Both tandem repeat and...