Search results | J. Murrey Atkins Library

Title: Microspherical Photonics for Enhancing Resolution of Optical Microscopy and Sensitivity of Focal Plane Arrays
Author: Brettin, Aaron
Date Created: 2018
Subjects--Topical: Optics
Description: It is shown that the resolution of virtual images of dye-doped dielectric nanospheres obtained through dielectric microspheres can be increased beyond the classical diffraction limit by decreasing the period of nanoplasmonic array used for localiz...

Title: ESSENTIAL DYNAMICS OF PROTEINS USING GEOMETRICAL SIMULATIONS AND SUBSPACE ANALYSIS
Author: David, Charles
Date Created: 2012
Subjects--Topical: Physics, Bioinformatics, Biophysics
Description: Essential dynamics is the application of principal component analysis to a dynamic trajectory derived from a simulation protocol in order to extract biologically relevant information contained in the high dimensional data. In this work, we apply t...

Title: Development of Silica Based Nanoparticles for Multimodal Therapeutic Delivery
Author: Vadarevu, Hemapriyadarshini
Date Created: 2022
Subjects--Topical: Nanoscience
Description: Chronic diseases like cancer are characterized by complex interactions between multiple pathways leading to treatment resistance and invasiveness. Repeated cycles of cytotoxic monotherapies are susceptible to drug resistance induced by the upregul...

Title: DO DYNAMIC ALLOSTERIC EFFECTS OCCUR IN IGG4 ANTIBODIES?
Author: Baker, Lonnie
Date Created: 2020
Subjects--Topical: Bioinformatics, Biophysics
Description: Antibodies are large, multi-chain proteins which play a critical roll in the func-tioning of vertebrate immune systems. Immune effector cells which are responsiblefor the destruction of foreign antigens do not randomly target molecules but rely on...

Title: Employing Surface Plasmon Resonances to Boost Effectiveness of Multiple Exciton Generation in Lead-Based Quantum Dots
Author: Dipple, Kathleen
Date Created: 2019
Subjects--Topical: Nanoscience
Description: Harvesting the sun’s energy at a high efficiency and low cost is a vital step towards replacing fossil fuels. Colloidal quantum dots (QDs) are promising materials that have great potential for solar applications due to their size dependent optical...

Title: Elucidating Dynamic Mechanisms for Extended Spectrum Antibiotic Resistance in Class A Beta-Lactamase through Machine Learning on Molecular Dynamics Simulations
Author: Avery, Christopher
Date Created: 2019
Subjects--Topical: Biophysics, Physics
Description: Beta-lactamase is a protein which is produced in bacteria and is a primary cause of antibiotic resistance to Beta Lactam antibiotics. Beta Lactams are among the most common types of antibiotics (including penicillin) and thus understanding the res...

Title: Mass Spectrometric Protein Footprinting of Conformational Changes Induced by Chromatographic Surfaces
Author: Focke, Kimberly
Date Created: 2022
Subjects--Topical: Analytical chemistry, Biochemistry
Description: Reversed-phase liquid chromatography (RPLC) of intact proteins induces conformational changes due to the denaturing effects of both the hydrophobic stationary phase and the high-organic mobile phase, which can lead to poor recovery and badly disto...

Title: Complex Glycan Synthesis in Bacteria
Author: Wallen, Timothy
Date Created: 2019
Subjects--Topical: Chemistry
Description: Glycans, which are assembled through a process known as glycosylation, are critical for creating biological structures important for the function and vitality of bacterial cells. In order to study the synthesis of glycans, enzymes and intermediate...

Title: Blinking Correlation in Nanocrystal Quantum Dots Probed with Novel Laser Scanning Confocal Microscopy Methods
Author: Hefti, Ryan
Date Created: 2013
Subjects--Topical: Nanoscience, Physics
Description: Semiconductor quantum dots have a vast array of applications: as fluorescent labels in biological systems, as physical or chemical sensors, as components in photovoltaic technology, and in display devices. An attribute of nearly every quantum dot ...

Title: Bohmian Trajectories of Interacting Particles Trapped in a Two-dimensional Harmonic Well
Author: Keithly, Gregory
Date Created: 2021
Subjects--Topical: Physics
Description: Bohmian mechanics is an alternate formalism of quantum mechanics that posits a particle is always existent, and furthermore there is a separate entity describing a wave-like disturbance in space and time, governed by the Schrodinger equation, that...

Title: Chemoenzymatic Preparation of Probes for in vitro and Cellular Elucidation of Complex Bacteria Polysaccharides
Author: Reid, Amanda
Date Created: 2021
Subjects--Topical: Microbiology, Biochemistry, Analytical chemistry
Description: Bacteria play a major role in our health and wellbeing. The microbe-host interaction is often mediated by sugar polymers at the cell surface. An incredibly diverse amount of glycan variation exists throughout these structures, which makes identifi...

Title: ORGANIZATION OF BIOMOLECULES IN A 3-DIMENSIONAL SPACE
Author: Sajja, Sameer
Date Created: 2019
Subjects--Topical: Nanotechnology, Biochemistry
Description: The human body operates using various stimuli-responsive mechanisms, dictating biological activity via reaction to external cues. Hydrogels are networked hydrophilic polymeric materials that offer the potential to recreate aqueous environments wit...

Title: ORGANIZATION OF BIOMOLECULES IN A 3-DIMENSIONAL SPACE
Author: Sajja, Sameer
Date Created: 2019
Subjects--Topical: Biochemistry
Description: The human body operates using various stimuli-responsive mechanisms, dictating biological activity via reaction to external cues. Hydrogels are networked hydrophilic polymeric materials that offer the potential to recreate aqueous environments wit...

Title: SUBSURFACE THERMAL COAGULATION OF TISSUES USING NEAR INFRARED LASERS
Author: Chang, Chun-Hung
Date Created: 2017
Subjects--Topical: Optics, Biophysics, Biomedical engineering
Description: Noninvasive laser therapy is currently limited primarily to cosmetic dermatological applications such as skin resurfacing, hair removal, tattoo removal and treatment of vascular birthmarks. In order to expand applications of noninvasive laser ther...

Title: Immunostimulatory Properties of Nucleic Acid Nanoparticles
Author: Halman, Justin
Date Created: 2020
Subjects--Topical: Nanoscience
Description: Nucleic acids (DNA and RNA) are ubiquitous biomolecules found throughout all living organisms. They can act as genetic information storage and messengers, enzymes, molecular switches, and much more. Although DNA is used almost exclusively for its ...

Title: Characterization of Dynamic and Functional Nucleic Acid Based Systems
Author: Beasock, Damian
Date Created: 2023
Subjects--Topical: Nanoscience
Description: Nucleic acids are highly integrated into molecular biology and exhibit very interesting character. They have immense engineering potential to improve human health and influence molecular systems. Consequently, these biopolymers are the quintessent...