Search results
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Title
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Complex Glycan Synthesis in Bacteria
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Author
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Wallen, Timothy
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Date Created
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2019
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Subjects--Topical
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Chemistry
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Description
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Glycans, which are assembled through a process known as glycosylation, are critical for creating biological structures important for the function and vitality of bacterial cells. In order to study the synthesis of glycans, enzymes and intermediate...
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Title
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DO DYNAMIC ALLOSTERIC EFFECTS OCCUR IN IGG4 ANTIBODIES?
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Author
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Baker, Lonnie
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Date Created
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2020
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Subjects--Topical
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Bioinformatics, Biophysics
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Description
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Antibodies are large, multi-chain proteins which play a critical roll in the func-tioning of vertebrate immune systems. Immune effector cells which are responsiblefor the destruction of foreign antigens do not randomly target molecules but rely on...
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Title
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Development of Silica Based Nanoparticles for Multimodal Therapeutic Delivery
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Author
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Vadarevu, Hemapriyadarshini
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Date Created
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2022
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Subjects--Topical
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Nanoscience
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Description
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Chronic diseases like cancer are characterized by complex interactions between multiple pathways leading to treatment resistance and invasiveness. Repeated cycles of cytotoxic monotherapies are susceptible to drug resistance induced by the upregul...
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Title
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ESSENTIAL DYNAMICS OF PROTEINS USING GEOMETRICAL SIMULATIONS AND SUBSPACE ANALYSIS
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Author
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David, Charles
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Date Created
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2012
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Subjects--Topical
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Physics, Bioinformatics, Biophysics
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Description
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Essential dynamics is the application of principal component analysis to a dynamic trajectory derived from a simulation protocol in order to extract biologically relevant information contained in the high dimensional data. In this work, we apply t...
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Title
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Immunostimulatory Properties of Nucleic Acid Nanoparticles
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Author
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Halman, Justin
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Date Created
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2020
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Subjects--Topical
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Nanoscience
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Description
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Nucleic acids (DNA and RNA) are ubiquitous biomolecules found throughout all living organisms. They can act as genetic information storage and messengers, enzymes, molecular switches, and much more. Although DNA is used almost exclusively for its ...
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Title
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ORGANIZATION OF BIOMOLECULES IN A 3-DIMENSIONAL SPACE
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Author
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Sajja, Sameer
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Date Created
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2019
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Subjects--Topical
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Nanotechnology, Biochemistry
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Description
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The human body operates using various stimuli-responsive mechanisms, dictating biological activity via reaction to external cues. Hydrogels are networked hydrophilic polymeric materials that offer the potential to recreate aqueous environments wit...
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Title
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ORGANIZATION OF BIOMOLECULES IN A 3-DIMENSIONAL SPACE
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Author
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Sajja, Sameer
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Date Created
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2019
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Subjects--Topical
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Biochemistry
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Description
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The human body operates using various stimuli-responsive mechanisms, dictating biological activity via reaction to external cues. Hydrogels are networked hydrophilic polymeric materials that offer the potential to recreate aqueous environments wit...
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Title
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SUBSURFACE THERMAL COAGULATION OF TISSUES USING NEAR INFRARED LASERS
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Author
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Chang, Chun-Hung
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Date Created
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2017
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Subjects--Topical
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Optics, Biophysics, Biomedical engineering
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Description
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Noninvasive laser therapy is currently limited primarily to cosmetic dermatological applications such as skin resurfacing, hair removal, tattoo removal and treatment of vascular birthmarks. In order to expand applications of noninvasive laser ther...