Search results | J. Murrey Atkins Library

Title: A SINGLE-PIXEL HYPERSPECTRAL IMAGING SYSTEM FOR CANCER MARGIN DETECTION
Author: Peller, Joseph
Date Created: 2018
Subjects--Topical: Optics, Physics
Description: We have developed a hyperspectral imaging (HSI) system based on a single pixel camera design to detect differences in tissue properties based on the optical reflectance and autofluorescence spectra of the tissue. The long-term goal of this project...

Title: APE2 is a Critical Regulator of the DNA Damage Response to Maintain Genome Integrity in Mammalian Cells
Author: HOSSAIN, MD AKRAM
Date Created: 2021
Subjects--Topical: Molecular biology, Biology, Cytology
Description: The maintenance of genome integrity and fidelity is essential for the proper function and survival of all organisms. Recent studies have revealed that APE2 is required for the activation of an ATR-Chk1 DNA damage response (DDR) pathway in response...

Title: DATA ANALYSIS WORKFLOW FOR GAS CHROMATOGRAPHY MASS SPECTROMETRY-BASED METABOLOMICS STUDIES
Author: Ni, Yan
Date Created: 2014
Subjects--Topical: Bioinformatics
Description: Metabolomics has emerged as an integral part of systems biology research that attempts to comprehensively study low molecular weight organic and inorganic metabolites under certain conditions within a biological system. Technological advances in t...

Title: Development of nanoparticle-based approaches for the treatment and imaging of pancreatic cancer
Author: Tarannum, Mubin
Date Created: 2020
Subjects--Topical: Nanoscience, Chemistry
Description: Pancreatic ductal adenocarcinoma (PDAC) is a type of exocrine pancreatic cancer which accounts for over 90% of cases. PDAC is the fourth-leading cause of cancer-related mortality in the United States with a 5-year survival rate of 9% with little t...

Title: FACTORS SHED BY BREAST TUMOR CELLS, TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME ACTIVITIES, AND THE GENERATION OF PRO-TUMOR MACROPHAGES
Author: Rego, Stephen
Date Created: 2013
Subjects--Topical: Biology
Description: The role of the tumor microenvironment, especially of tumor associated macrophages (TAMs), in the progression and metastatic spread of breast cancer is well established. TAMs are activated in the breast tumor microenvironment to express primarily ...

Title: FAULT-TOLERANT DESIGN FOR CONTINUOUS REAL-TIME MONITORING AND MODULATION OF THE HUMAN BRAIN
Author: Acharya, Ipsita
Date Created: 2015
Subjects--Topical: Electrical engineering, Biomedical engineering
Description: An era of brain implantable devices has been ushered in recent years. These devices are currently being used to treat neurological disorders such as Parkinson's depression and epilepsy and are increasingly being proposed for a wide range of neurol...

Title: FREQUENCY INDEPENDENT ANTENNAS INTERACTED ULTRA-WIDE BAND (UWB) ARTIFICIAL MAGNETIC CONDUCTOR (AMC) FOR 5G MILLIMETER WAVE WIRELESS COMMUNICATION APPLICATIONS
Author: Wang, Xuehe
Date Created: 2019
Subjects--Topical: Electrical engineering
Description: Fifth generation (5G) wireless communication is on the horizon and presents opportunities for significant technological advancement for years to come. As part of this important technology, millimeter wave communication has become a very important ...

Title: HOST FACTORS CONTROLLING VIRUS INFECTION: IMPLICATIONS FOR ANTIVIRALS AND VIROTHERAPY
Author: Shah, Nirav
Date Created: 2013
Subjects--Topical: Virology, Oncology
Description: Viruses are obligate intracellular parasites rely heavily on host components and pathways for their replication. Studying different cellular factors affecting viral infection can enable us to identify novel drug targets, improve current antiviral ...

Title: Hydrogen Sulfide Modulates Hepatic Oxygen Availability and Microcirculation during Sepsis
Author: Norris, Eric
Date Created: 2012
Subjects--Topical: Biology, Physiology
Description: A mismatch between O_{2_{supply and demand leads to the development of tissue hypoxia which contributes to hepatic dysfunction and injury during sepsis. Previously, we reported that hepatic microcirculatory failure is a major contributor to hypoxia a...}}

Title: MACROPHAGES EXPRESSING NEUROPILIN-1 AND BREAST TUMOR PROGRESSION
Author: Helms, Rachel
Date Created: 2015
Subjects--Topical: Biology
Description: Human breast carcinoma is the most commonly diagnosed cancer in women in the United States with patient mortality primarily resulting from metastasis of breast cancer cells to distant organs. Immune cells, including macrophages, are involved in ca...

Title: Nonsegmented negative strand RNA viruses: viral RNA cap methylation and potential applications as an anticancer therapy
Author: Murphy, Andrea
Date Created: 2012
Subjects--Topical: Virology, Biology
Description: The viruses of the order Mononegavirales include important human, animal, and plant pathogens and additionally, have great potential as vaccine, oncolytic and gene therapy vectors. This dissertation focuses on two prototypic Mononegavirales, vesic...

Title: Periostin and TGFBI in Breast Cancer Progression
Author: Phelps, Michelle
Date Created: 2015
Subjects--Topical: Biology, Cytology
Description: Dynamic interactions between cancer cells, supportive stromal cells, the extracellular matrix (ECM), and the immune system are critical to breast cancer progression. Periostin is an ECM protein correlated to poor outcomes in breast cancer. Periost...

Title: The Genomics Revolution and Its Marketing Implications
Author: McGuire, Layne
Date Created: 2023
Subjects--Topical: Marketing, Genetics
Description: Genetic characteristics drive around 50% of human behavioral traits. The capacity of genes to help predict consumer behavioral traits may far exceed that of current behavioral and Big Data paradigms. Genomic data thus represents a seminal paradigm...

Title: Topoisomerase II Inhibitors Induce an Illegitimate Genome Rearrangement Common in Infant Leukemia
Author: Bariar, Bhawana
Date Created: 2013
Subjects--Topical: Molecular biology
Description: Infant acute leukemias account for ~30% of all malignancy seen in childhood across the Western world. They are aggressive and characterized by rapid onset shortly after birth. The majority of these have rearrangements involving the MLL (mixed line...