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Hepatic Stellate Cell Transdifferentiation: Pro-fibrogenic Effectors
Title
Hepatic Stellate Cell Transdifferentiation: Pro-fibrogenic Effectors
Author
Lakner, Ashley
Date Created
2011
Subjects--Topical
Molecular biology, Biology
Description
Hepatic fibrosis is a significant cause of morbidity and mortality worldwide and can be described as exacerbated wound-healing marked by excessive deposition of extracellular matrix components, predominantly type I collagen. Chronic injury stimula...
INTERLEUKIN-2 IN AQUEOUS AND LIPID ENVIRONMENTS: UNDERSTANDING MOLECULAR INTERACTIONS THAT IMPACT PHARMACEUTICAL FORMULATION DEVELOPMENT
Title
INTERLEUKIN-2 IN AQUEOUS AND LIPID ENVIRONMENTS: UNDERSTANDING MOLECULAR INTERACTIONS THAT IMPACT PHARMACEUTICAL FORMULATION DEVELOPMENT
Author
Vrikkis, Regina
Date Created
2013
Subjects--Topical
Mechanical engineering, Biomedical engineering, Pharmacy--Research
Description
The continued development of pharmaceutical recombinant proteins as therapeutics necessitates a full understanding of the biomolecular interactions impacting structural and functional protein stability within different environments. Two such envir...