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Examining the Contribution of the DNA Damage Response to Sepsis Survivor Myelosuppression
Title
Examining the Contribution of the DNA Damage Response to Sepsis Survivor Myelosuppression
Author
Huff, Laura
Date Created
2020
Subjects--Topical
Immunology, Biology, Pathology
Description
A large portion of patients who survive sepsis, a life-threatening hyperinflammatory response to infection resulting in organ dysfunction, experience a higher risk of mortality than non-septic patients. Innate immune cells of sepsis survivors exhi...
Inflammation, NLRP3 Inflammasomes, Macrophages and Breast Cancer Progression
Title
Inflammation, NLRP3 Inflammasomes, Macrophages and Breast Cancer Progression
Author
Holtzman , Katherine
Date Created
2021
Subjects--Topical
Biology, Immunology, Oncology
Description
One in 8 women will be diagnosed with breast cancer in their lifetime and while breast cancer mortality has declined since the 1980s, it remains the 2nd leading cause of cancer-related deaths among women. Standard of care is determined by anatomic...
Study of the Intracellular Protein Tau and its Relationship with Kunjin Virus and Neurodegenerative Diseases
Title
Study of the Intracellular Protein Tau and its Relationship with Kunjin Virus and Neurodegenerative Diseases
Author
Lotz, Sarah
Date Created
2022
Subjects--Topical
Neurosciences, Immunology, Virology
Description
Neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis, comprise a family of disorders characterized by progressive loss of nervous system function. Neuroinflammation is increasingly recogni...