Sporadic Amyotrophic lateral sclerosis (sALS) is a complex, invariably fatal, disease with a poorly understood cause, despite many studies. Diagnostic biomarkers that precede active symptoms would be an immense help to clinicians, for patient mana...
Microarray technology is a commonly used tool in biomedical research for assessing global gene expression, surveying DNA sequence variations, and studying alternative gene splicing. Given the wide range of applications of this technology, comprehe...
Pathway enrichment analysis models (PEM) are biological inference approaches that leverage annotated bio-molecular functions for interpreting the underlying processes of gene expression profiles from high-throughput genomic data. Common PEMs negle...
