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A VISUAL ANALYTICS APPROACH TO FEATURE DISCOVERY AND SUBSPACE EXPLORATION IN PROTEIN FLEXIBILITY MATRICES
Title
A VISUAL ANALYTICS APPROACH TO FEATURE DISCOVERY AND SUBSPACE EXPLORATION IN PROTEIN FLEXIBILITY MATRICES
Author
Barlowe, Scott
Date Created
2011
Subjects--Topical
Computer science, Bioinformatics
Description
The vast amount of information generated by domain scientists makes the transitionfrom data to knowledge difficult and often impedes important discoveries. Forexample, the knowledge gained from protein flexibility data sets can speed advancesin ge...
ESSENTIAL DYNAMICS OF PROTEINS USING GEOMETRICAL SIMULATIONS AND SUBSPACE ANALYSIS
Title
ESSENTIAL DYNAMICS OF PROTEINS USING GEOMETRICAL SIMULATIONS AND SUBSPACE ANALYSIS
Author
David, Charles
Date Created
2012
Subjects--Topical
Physics, Bioinformatics, Biophysics
Description
Essential dynamics is the application of principal component analysis to a dynamic trajectory derived from a simulation protocol in order to extract biologically relevant information contained in the high dimensional data. In this work, we apply t...
Stability, resistance and change in mammalian microbiota and their associations with host health
Title
Stability, resistance and change in mammalian microbiota and their associations with host health
Author
Spencer, Melanie
Date Created
2011
Subjects--Topical
Biology, Microbiology, Bioinformatics
Description
What is the nature of a complex organism? Metagenomic research and its insights into biosystem function have fundamentally altered the answer to this question. High-throughput sequencing technology has revealed the multitude of microbes that live ...
Structural analysis of protein-DNA binding specificity and its application to protein-DNA docking assessment
Title
Structural analysis of protein-DNA binding specificity and its application to protein-DNA docking assessment
Author
Corona de la Fuente, Rosario
Date Created
2016
Subjects--Topical
Bioinformatics
Description
DNA-binding proteins are involved in essential biological processes including gene expression, DNA packaging and DNA repair. They bind to DNA target sequences with different degrees of binding specificity, ranging from highly specific to non-speci...
The evolution of flavonoid pathway in legumes
Title
The evolution of flavonoid pathway in legumes
Author
Safari, Sajedeh
Date Created
2016
Subjects--Topical
Bioinformatics
Description
Considering the ever growing world population as well as climate change, it has become essential to improve crops in order to reach higher yields, more tolerance to pests and droughts, and better adaptation to different environments. The advanceme...