Search results | J. Murrey Atkins Library

Title: A Detailed Description of Keldysh's Model of Photoionization
Author: Darden, Kenan
Date Created: 2023
Subjects--Topical: Physics, Optics, Quantum theory
Description: Leonid Keldysh’s 1965 paper "Ionization in the Field of a Strong Electromagnetic Wave" contains useful and simple-to-implement equations predicting the rate of photoionization in both atomic gasses and general crystalline solids. Crucially, his re...

Title: ELUCIDATING THE MOLECULAR BASIS OF INHIBITION OF ENZYMES ESSENTIAL FOR BATERIALVIRULENCE: THE ACTIVITY OF THREE GLYCOSYLTRANSFERASES AND A POTENTIAL DRUG TARGET, UNDECAPRENYL PYROPHOSPHATE SYNTHASE
Author: Okwei, Elleansar
Date Created: 2016
Subjects--Topical: Chemistry, Biology, Biochemistry
Description: The fight against bacterial infection is one of the most important branches of modern medicine. Due to the emergence of strains of antibiotic-resistant bacteria, researchers have been presented with complex challenges in an effort to combat these ...

Title: Green Synthesis of Cellulose Graft Copolymers for Anion Exchange Water Purification
Author: Schmal, Stephen
Date Created: 2022
Subjects--Topical: Chemistry
Description: This thesis describes the synthesis and characterization of novel cellulose graft copolymers that are used for the purification of drinking water. These nanomaterials function as bottle-brush anion-exchange resins with repeating quaternary ammoniu...

Title: Halogenated Tags for the Investigation of Enzyme Specificity
Author: Houde, Hailey
Date Created: 2023
Subjects--Topical: Biochemistry, Chemistry
Description: The bacterial enzyme undecaprenyl pyrophosphate synthase (UppS) is present in most prokaryotes and is needed for bacterial survival. UppS produces the essential lipid carrier, bactoprenyl monophosphate (BP). BP is critical for the structural integ...

Title: Implementation of Focusing Light through Highly Scattering Media via Sequential Algorithm Based Wavefront Shaping
Author: Williams, Desmond
Date Created: 2019
Subjects--Topical: Physics
Description: Propagation of light in communications, medicine, and science is hindered by the phenomenon of optical scattering. Methods to overcome this physical limitation have and continue to be researched. This work attempts to implement the method of wavef...

Title: Light-assisted drying (LAD) for anhydrous preservation of biologics: processing sample volumes comparable to a therapeutic dose
Author: Furr, Daniel
Date Created: 2022
Subjects--Topical: Physics
Description: Protein-based products have been developed to treat a range of conditions and are used in vaccines and assays. A challenge in the development of these products is maintaining the protein in the folded state during processing and storage. The most ...

Title: Moisture sorption behavior, stability, and protein formulation characteristics of a trehalose choline chloride eutectic composition
Author: Burgin, Tiffany
Date Created: 2017
Subjects--Topical: Mechanical engineering, Materials science, Biochemistry
Description: Protein based drugs and therapeutics are an important treatment for many life-threatening diseases but they can also be extremely expensive. The unique 3-dimensional structure of a protein is responsible for its function but also contributes to it...

Title: PROTEIN-PROTEIN INTERACTION OF PAI-H19Y MUTANT OF THE SLEEPING BEAUTY TRANSPOSASE
Author: Yan, Chenbo
Date Created: 2020
Subjects--Topical: Biophysics, DNA
Description: Due to the substantial interest in developing transposon technology for gene delivery and gene therapy, the Sleeping Beauty (SB) transposon system, the most active transposon in the vertebrate species, has been extensively studied. The SB transpos...

Title: Physics Informed Machine Learning Models for PDEs with Applications to Laser Bioeffects
Author: Seman, Matthew
Date Created: 2023
Subjects--Topical: Artificial intelligence, Physics
Description: Recently, advances in the efficiency of gradient calculation algorithms have sparked anexpansion of neural network applications, particularly in the field of approximating partial differential equation (PDE) solutions. Among the most novel and eff...

Title: Quantifying the Binding Affinities of the PAI-H19Y Mutant of Sleeping Beauty Transposase to DNA
Author: Arango, Maria
Date Created: 2022
Subjects--Topical: Physics
Description: The Sleeping Beauty (SB) transposon system is the leading and only DNA transposon-based gene-delivery vehicle that has been adapted for human gene therapy. The SB system consists of a transposon DNA flanked by inverted terminal repeats (ITRs) and ...

Title: RED FLUORESCENCE IN BOVINE SERUM ALBUMIN – GOLD COMPLEXES
Author: Dixon, Jacob
Date Created: 2019
Subjects--Topical: Optics, Physics
Description: Bovine serum albumin (BSA)-gold (Au) complexes have been studied in great detail due to their unique red fluorescent (λem = 640 nm) properties, since being initially described by Xie et al. (J. Am. Chem. Soc. 2009, 131, 888-889) as a Au25 nanoclus...

Title: STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE H19Y MUTATED PRIMARY DNA RECOGNITION SUBDOMAIN OF SLEEPING BEAUTY TRANSPOSASE
Author: Leighton, Gage
Date Created: 2017
Subjects--Topical: Physics, Chemistry, Physical and theoretical, Biophysics
Description: The Sleeping Beauty transposon system, consisting of the transposon DNA and the transposase enzyme, is a member of the Tc1/mariner family of DNA transposons. Although it is an important tool in genetic applications and has been adapted for human g...

Title: Spatially Resolved Photoluminescence Lifetime Mapping in the Vicinity of Extended Defects in Semiconductors Using a Time Correlated Single Photon Counting System and Confocal Photoluminescence Microscopy
Author: Mode, Timothy
Date Created: 2016
Subjects--Topical: Optics, Physics
Description: Photoluminescence mapping and time resolved photoluminescence imaging have previously been used to study charge carrier dynamics in bulk semiconductors. Recently, our research group has used spatially resolved PL mapping to examine and model carri...

Title: The Application of Light-Assisted Drying to the Thermal Stabilization of Nucleic Acid Nanoparticles
Author: Lam, Phuong Anh
Date Created: 2021
Subjects--Topical: Physics
Description: Cold storage can be challenging and expensive for the transportation and storage of biologics. We are developing a new processing technique, light-assisted drying (LAD), to prepare biologics for anhydrous storage in a trehalose amorphous solid mat...