- Jacobs, Donald (x)
- Number of Eigenvalues (x)
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- Title
- A Detailed Description of Keldysh's Model of Photoionization
- Author
- Darden, Kenan
- Date Created
- 2023
- Subjects--Topical
- Physics, Optics, Quantum theory
- Description
- Leonid Keldysh’s 1965 paper "Ionization in the Field of a Strong Electromagnetic Wave" contains useful and simple-to-implement equations predicting the rate of photoionization in both atomic gasses and general crystalline solids. Crucially, his re...
- Title
- A VISUAL ANALYTICS APPROACH TO FEATURE DISCOVERY AND SUBSPACE EXPLORATION IN PROTEIN FLEXIBILITY MATRICES
- Author
- Barlowe, Scott
- Date Created
- 2011
- Subjects--Topical
- Computer science, Bioinformatics
- Description
- The vast amount of information generated by domain scientists makes the transitionfrom data to knowledge difficult and often impedes important discoveries. Forexample, the knowledge gained from protein flexibility data sets can speed advancesin ge...
- Title
- ALGORITHMS FOR STRUCTURE BASED-PREDICTION OF TRANSCRIPTION FACTOR BINDING SITES
- Author
- Farrel, Alvin
- Date Created
- 2016
- Subjects--Topical
- Computer science, Biology, Bioinformatics
- Description
- Transcription factors (TFs) regulate gene expression through binding to specific target DNA sites. Accurate annotation of transcription factor binding sites (TFBSs) at genome scale represents an essential step toward our understanding of gene regu...
- Title
- Asymptotic Normality of Higher Order Turing Formulae
- Author
- Chang, Jie
- Date Created
- 2022
- Subjects--Topical
- Mathematics
- Description
- Higher order Turing formulae, denoted as Tr for r ∈ Z+, are a powerful result allowing one to estimate the total probability associated with words from a random piece of writing, which have been observed exactly r times in a random sample. In part...
- Title
- Design, Synthesis, Characterization and Simulation of Polyhedral Oligomeric Silsesquioxane Porphyrin Molecules to Fabricate Self-Assembled Nanoparticles and Their Use for Photodynamic Therapy
- Author
- Loman-Cortes, Paula
- Date Created
- 2021
- Subjects--Topical
- Nanoscience
- Description
- PAULA LOMAN-CORTES. Design, Synthesis, Characterization and Simulation of Polyhedral Oligomeric Silsesquioxane Porphyrin Molecules to Fabricate Self-Assembled Nanoparticles and Their Use for Photodynamic Therapy. (Under the direction of DR JUAN L ...
- Title
- ELUCIDATING THE MOLECULAR BASIS OF INHIBITION OF ENZYMES ESSENTIAL FOR BATERIALVIRULENCE: THE ACTIVITY OF THREE GLYCOSYLTRANSFERASES AND A POTENTIAL DRUG TARGET, UNDECAPRENYL PYROPHOSPHATE SYNTHASE
- Author
- Okwei, Elleansar
- Date Created
- 2016
- Subjects--Topical
- Chemistry, Biology, Biochemistry
- Description
- The fight against bacterial infection is one of the most important branches of modern medicine. Due to the emergence of strains of antibiotic-resistant bacteria, researchers have been presented with complex challenges in an effort to combat these ...
- Title
- Fracture properties of graphene-like two-dimensional materials and topology optimization through neural networks for coupled thermo-mechanical problems
- Author
- Shishir, Md Imrul Reza
- Date Created
- 2022
- Subjects--Topical
- Mechanical engineering, Mechanics, Materials science
- Description
- Part I: Study of fracture properties of graphene--like two--dimensional materials using molecular dynamics (MD) simulationsGraphene is a monoatomic thick sheet of sp2-hybridized carbon atoms tightly packed in a honeycomb lattice structure. It has ...
- Title
- Green Synthesis of Cellulose Graft Copolymers for Anion Exchange Water Purification
- Author
- Schmal, Stephen
- Date Created
- 2022
- Subjects--Topical
- Chemistry
- Description
- This thesis describes the synthesis and characterization of novel cellulose graft copolymers that are used for the purification of drinking water. These nanomaterials function as bottle-brush anion-exchange resins with repeating quaternary ammoniu...
- Title
- Halogenated Tags for the Investigation of Enzyme Specificity
- Author
- Houde, Hailey
- Date Created
- 2023
- Subjects--Topical
- Biochemistry, Chemistry
- Description
- The bacterial enzyme undecaprenyl pyrophosphate synthase (UppS) is present in most prokaryotes and is needed for bacterial survival. UppS produces the essential lipid carrier, bactoprenyl monophosphate (BP). BP is critical for the structural integ...
- Title
- Implementation of Focusing Light through Highly Scattering Media via Sequential Algorithm Based Wavefront Shaping
- Author
- Williams, Desmond
- Date Created
- 2019
- Subjects--Topical
- Physics
- Description
- Propagation of light in communications, medicine, and science is hindered by the phenomenon of optical scattering. Methods to overcome this physical limitation have and continue to be researched. This work attempts to implement the method of wavef...
- Title
- Light-assisted drying (LAD) for anhydrous preservation of biologics: processing sample volumes comparable to a therapeutic dose
- Author
- Furr, Daniel
- Date Created
- 2022
- Subjects--Topical
- Physics
- Description
- Protein-based products have been developed to treat a range of conditions and are used in vaccines and assays. A challenge in the development of these products is maintaining the protein in the folded state during processing and storage. The most ...
- Title
- Moisture sorption behavior, stability, and protein formulation characteristics of a trehalose choline chloride eutectic composition
- Author
- Burgin, Tiffany
- Date Created
- 2017
- Subjects--Topical
- Mechanical engineering, Materials science, Biochemistry
- Description
- Protein based drugs and therapeutics are an important treatment for many life-threatening diseases but they can also be extremely expensive. The unique 3-dimensional structure of a protein is responsible for its function but also contributes to it...
- Title
- On Accelerating Road Vehicle Aerodynamics
- Author
- Peters, Brett
- Date Created
- 2018
- Subjects--Topical
- Mechanical engineering, Aerospace engineering, Fluid mechanics
- Description
- Road vehicle aerodynamics are primarily focused on developing and modeling performance at steady-state conditions, although this does not fully encompass the entire operating envelope. Considerable vehicle acceleration and deceleration occurs duri...
- Title
- On the Infinite Divisibility and Non Infinite Divisibility of Certain Classes of Random Variables
- Author
- Stukes, George
- Date Created
- 2023
- Subjects--Topical
- Mathematics
- Description
- In this dissertation we present new results on the classification of limit distributions of random geometric processes. In particular, that develop on the work of Penrose and Wade, who were the first to document the phenomenon of infinite divisibi...
- Title
- PROTEIN-PROTEIN INTERACTION OF PAI-H19Y MUTANT OF THE SLEEPING BEAUTY TRANSPOSASE
- Author
- Yan, Chenbo
- Date Created
- 2020
- Subjects--Topical
- Biophysics, DNA
- Description
- Due to the substantial interest in developing transposon technology for gene delivery and gene therapy, the Sleeping Beauty (SB) transposon system, the most active transposon in the vertebrate species, has been extensively studied. The SB transpos...
- Title
- Physics Informed Machine Learning Models for PDEs with Applications to Laser Bioeffects
- Author
- Seman, Matthew
- Date Created
- 2023
- Subjects--Topical
- Artificial intelligence, Physics
- Description
- Recently, advances in the efficiency of gradient calculation algorithms have sparked anexpansion of neural network applications, particularly in the field of approximating partial differential equation (PDE) solutions. Among the most novel and eff...
- Title
- Quantifying the Binding Affinities of the PAI-H19Y Mutant of Sleeping Beauty Transposase to DNA
- Author
- Arango, Maria
- Date Created
- 2022
- Subjects--Topical
- Physics
- Description
- The Sleeping Beauty (SB) transposon system is the leading and only DNA transposon-based gene-delivery vehicle that has been adapted for human gene therapy. The SB system consists of a transposon DNA flanked by inverted terminal repeats (ITRs) and ...
- Title
- RED FLUORESCENCE IN BOVINE SERUM ALBUMIN – GOLD COMPLEXES
- Author
- Dixon, Jacob
- Date Created
- 2019
- Subjects--Topical
- Optics, Physics
- Description
- Bovine serum albumin (BSA)-gold (Au) complexes have been studied in great detail due to their unique red fluorescent (λem = 640 nm) properties, since being initially described by Xie et al. (J. Am. Chem. Soc. 2009, 131, 888-889) as a Au25 nanoclus...
- Title
- REGULATION OF ACTOMYOSIN ATPASE
- Author
- Ge, Jinghua
- Date Created
- 2016
- Subjects--Topical
- Optics, Physics, Biophysics
- Description
- Myosin is a molecular motor that converts chemical energy to mechanical energy, thus generating force and movement in muscles and cells. Myosin interacts with two ligands, ATP (fuel) and actin filaments (motor’s tracks). Actomyosin interaction is ...
- Title
- RETENTION OF THE AMORPHOUS STATE OF TREHALOSE AT HIGH RELATIVE HUMIDITY USING ORGANIC SALT ADDITIVES: A MECHANISTIC UNDERSTANDING
- Author
- Ziaei, Shima
- Date Created
- 2018
- Subjects--Topical
- Materials science, Pharmacy--Research, Bioengineering
- Description
- The glassy or amorphous solid state of trehalose has been utilized in the food and pharmaceutical industry to immobilize and stabilize sensitive molecules and it is increasingly being explored for the preservation of biologics. Retention of the gl...