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Cell Type-Specific Double Strand Break Repair: An Inter-Chromosomal Homologous Recombination Study Using the Rainbow Mouse Model
Title
Cell Type-Specific Double Strand Break Repair: An Inter-Chromosomal Homologous Recombination Study Using the Rainbow Mouse Model
Author
Lalwani, Kiran
Date Created
2023
Subjects--Topical
Molecular biology, Cytology, Developmental biology
Description
Faithful repair of DNA lesions is central to maintaining genomic integrity. Illegitimate repair of chromosomal DNA damage, especially double-strand breaks (DSBs), can lead to mutations and genome rearrangements. Homologous recombination (HR) is a ...
The Potential for Genistein, a Topoisomerase II Inhibitor, to Induce Inter-Chromosomal Homologous Recombination.
Title
The Potential for Genistein, a Topoisomerase II Inhibitor, to Induce Inter-Chromosomal Homologous Recombination.
Author
French, Caroline
Date Created
2023
Subjects--Topical
Molecular biology
Description
Maintenance of genome integrity is important for preventing mutagenic events and preserving overall cell functionality. DNA damaging agents induce DNA double strand breaks (DSBs) that are repaired through repair pathways non-homologous end-joining...
The role of the dopaminergic system in the regulation of physical activity in mice
Title
The role of the dopaminergic system in the regulation of physical activity in mice
Author
Knab, Amy
Date Created
2009
Subjects--Topical
Molecular biology, Genetics, Physiology
Description
Physical activity (PA) is important to human health, and the genetic and biological regulating factors of physical activity are only beginning to be understood. The dopamine (DA) system has been shown to regulate motivation, and locomotor behavior...