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Long-term study of changes in microbiota in a Cystic Fibrosis patient
Title
Long-term study of changes in microbiota in a Cystic Fibrosis patient
Author
Stokell, Joshua
Date Created
2013
Subjects--Topical
Biology, Microbiology
Description
Application of culture-independent techniques have revealed the presence of more types of bacteria than were previously thought, which led to the current description of Cystic Fibrosis (CF) being a polymicrobial disease. We know this polymicrobial...
MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
Title
MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
Author
Grover, Priyanka
Date Created
2019
Subjects--Topical
Biology
Description
In 2019, Pancreatic Cancer (PC) is the 3rd leading cause of cancer-related deaths in the USA with 94% dying within 5 years of diagnosis. 90% of PC is Pancreatic Ductal Adenocarcinoma (PDA), of which >80% overexpress a hypo-glycosylated form the me...
NOVEL ROLES OF MICRORNAS IN HEPATITIS C
Title
NOVEL ROLES OF MICRORNAS IN HEPATITIS C
Author
Sendi, Hossein
Date Created
2013
Subjects--Topical
Virology, Biology
Description
Approximately, 170 million people are infected by hepatitis C virus (HCV) worldwide, and of these, nearly 85% will develop chronic hepatitis C (CHC). Despite finding new anti-viral treatment that increase response rate from 45 % to 65-70 %, invest...
Newly described cytosolic pattern recognition receptors mediate inflammatory glial responses to neurotropic viruses
Title
Newly described cytosolic pattern recognition receptors mediate inflammatory glial responses to neurotropic viruses
Author
Furr, Samantha
Date Created
2012
Subjects--Topical
Immunology, Biology
Description
The rapid onset of potentially lethal neuroinflammation is a defining feature of viral encephalitis. Glial cells are ideally positioned to respond to invading pathogens of the central nervous system (CNS) and produce key inflammatory mediators fol...
RECIPROCAL REGULATION OF MYC AND MICRORNA MIR-308 DURING DROSOPHILA EMBRYOGENESIS
Title
RECIPROCAL REGULATION OF MYC AND MICRORNA MIR-308 DURING DROSOPHILA EMBRYOGENESIS
Author
Daneshvar, Kaveh
Date Created
2012
Subjects--Topical
Molecular biology, Biology, Genetics
Description
Myc is a conserved transcription factor with a role in the regulation of genes that are involved in growth and development. The abundance of Myc protein in the cells must be exquisitely controlled to avoid growth abnormalities caused by too much o...
THE DEVELOPMENT OF NOVEL THERAPEUTICS IN PANCREATIC AND BREAST CANCERS: POTENTIAL ROLE OF MUC1
Title
THE DEVELOPMENT OF NOVEL THERAPEUTICS IN PANCREATIC AND BREAST CANCERS: POTENTIAL ROLE OF MUC1
Author
Besmer, Dahlia
Date Created
2013
Subjects--Topical
Biology
Description
Pancreatic ductal adenocarcinoma (PDA) is the 4th leading cause of cancer-related deaths in the US, and breast cancer (BC) contributes to ~40,000 deaths annually. The development of novel therapeutic agents for improving patient outcome is of para...
THE ROLE OF MUC1 IN REGULATION AND PROGRESSION OF CANCER
Title
THE ROLE OF MUC1 IN REGULATION AND PROGRESSION OF CANCER
Author
Sahraeimanouchehrabadi, Mahnaz
Date Created
2011
Subjects--Topical
Immunology, Biology, Oncology
Description
MUC1 is a heavily glycosylated transmembrane glycoprotein which is overexpressed and aberrantly glycosylated in most human carcinomas. MUC1 contains a large tandem repeat, a short transmembrane, and a small cytoplasmic tail. Both tandem repeat and...