- Gibas, Cynthia (x)
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Search results
- Title
- Assessment of Methods and Environmental Influence on the Nematostella Vectensis Microbiome
- Author
- Krueger, Quinton
- Date Created
- 2022
- Subjects--Topical
- Microbiology, Bioinformatics
- Description
- Cnidarians are a diverse clade of marine invertebrates that inhabit a variety of environments. The conditions of these habitats are becoming more extreme with the progression of time. These organisms associate with bacteria, which are composed of ...
- Title
- Common Dietary and Environmental Compounds Promote a Leukemic Translocation in Hematopoietic Stem Cells and Differentiated Cells
- Author
- Vestal, Carol
- Date Created
- 2016
- Subjects--Topical
- Molecular biology, Biology, Genetics
- Description
- Maternal exposure to topoisomerase II (topoII) inhibitors that are biochemically similar to the chemotherapeutic drug etoposide may promote infant acute leukemia. Several studies have shown that common dietary bioflavonoids as well as benzene meta...
- Title
- DATA ANALYSIS WORKFLOW FOR GAS CHROMATOGRAPHY MASS SPECTROMETRY-BASED METABOLOMICS STUDIES
- Author
- Ni, Yan
- Date Created
- 2014
- Subjects--Topical
- Bioinformatics
- Description
- Metabolomics has emerged as an integral part of systems biology research that attempts to comprehensively study low molecular weight organic and inorganic metabolites under certain conditions within a biological system. Technological advances in t...
- Title
- ELUCIDATING FUNCTIONAL MECHANISMS IN PROTEINS USING THE DISTANCE CONSTRAINT MODEL
- Author
- Singer, Christopher
- Date Created
- 2019
- Subjects--Topical
- Bioinformatics, Biophysics, Physics
- Description
- Protein thermodynamics has been shown to be insightful and illuminating to the functional mechanisms behind biological function. By characterizing proteins and protein families according to their enthalpy and entropy we can make inferences to the ...
- Title
- Emerging Challenges in Landfill Leachate Quality and Ability of Fungal Bioreactors to Address Them
- Author
- Rezaei Adaryani, Amirhossein
- Date Created
- 2021
- Subjects--Topical
- Environmental engineering
- Description
- Landfill sites, that are the ultimate depository of solid waste stream in most societies, have the potential to generate leachate containing a complex mixture of contaminants of emerging concern (CECs) such as pharmaceutical compounds, plasticizer...
- Title
- Hydrogen Sulfide Modulates Hepatic Oxygen Availability and Microcirculation during Sepsis
- Author
- Norris, Eric
- Date Created
- 2012
- Subjects--Topical
- Biology, Physiology
- Description
- A mismatch between O2 supply and demand leads to the development of tissue hypoxia which contributes to hepatic dysfunction and injury during sepsis. Previously, we reported that hepatic microcirculatory failure is a major contributor to hypoxia a...
- Title
- INVESTIGATING THE ECOLOGICAL, PATHOGENIC, AND DORMANT LIFESTYLES OF THE ESTUARINE BACTERIUM, VIBRIO VULNIFICUS
- Author
- Williams, Tiffany
- Date Created
- 2015
- Subjects--Topical
- Microbiology, Bioinformatics
- Description
- Vibrio vulnificus is ubiquitous in estuarine and coastal waters worldwide and associates naturally with a variety of aquatic organisms. Notably, it is a highly invasive human pathogen capable of causing septicemia and multi-organ failure in person...
- Title
- INVESTIGATING THE GENETIC BASIS OF GENE EXPRESSION USING EQTL TECHNIQUES
- Author
- Quitadamo, Andrew
- Date Created
- 2018
- Subjects--Topical
- Bioinformatics
- Description
- With advances in genome sequencing technology, datasets with large sample sizes can be generated relatively quickly and cheaply, especially compared to the past decade or so. We can utilize this data to analyze the associations between genetic var...
- Title
- Investigation and Analysis of Context Dependent Mutation Rates Contribution to Synonymous Mutation Codon Usage via Development of CDMAP.
- Author
- Patton, David
- Date Created
- 2022
- Subjects--Topical
- Bioinformatics, Molecular biology, Biometry
- Description
- Mutations play a pivotal role as a driver of genome evolution in organisms across the tree of life. However, site-specific mutation rates appear to have a non-uniform mutation rate and vary across the genome. Currently, site-specific variation has...
- Title
- Microbial Mutations - Accumulation in Microfluidics and Collateral Sensitivity
- Author
- Turner, Nathan
- Date Created
- 2023
- Subjects--Topical
- Bioinformatics
- Description
- Mutations are a primary source of genetic variation and a major driving force in evolution by influencing survivability (fitness), genetic disease, and the development of complex traits such as antibiotic resistance. However, studying the mutation...
- Title
- New Algorithms for Protein Structure Analysis: From Nonparametric Density Estimation to Characterization of Molecular Volume Spatial Distributions
- Author
- Farmer, Jenny
- Date Created
- 2018
- Subjects--Topical
- Bioinformatics, Biophysics, Physics
- Description
- The Flexibility and Stability Test (FAST) is a C++ class library designed in the early 2000’s to execute free energy decomposition and reconstitution operations applied to protein structures. The library has been substantially expanded to include ...
- Title
- Nutritive Knowledge Based Discovery: Enhancing Precision Nutrition Hypothesis Generation
- Author
- Trautman, Aaron
- Date Created
- 2022
- Subjects--Topical
- Bioinformatics, Nutrition, Information science
- Description
- Diet-related diseases like obesity and type-2 diabetes are on the rise. Precision nutrition, a way to tailor dietary requirements for each individual, is heralded as a solution to these problems. However, nutritional research is held within sparse...
- Title
- On Whole Genome Classifier Perforamnce in Relation to 16S Classifiers
- Author
- Johnson, James
- Date Created
- 2022
- Subjects--Topical
- Bioinformatics
- Description
- There is little consensus in the literature as to which approach for classification of Whole Genome Shotgun (WGS) sequences is most accurate unlike 16S classifiers that have had more time to mature. In this dissertation, two of the most popular cl...
- Title
- Pleiotropic effects on the transcriptome and genome of transgenic soybeans resulting from transgene integration and expression in seed tissue
- Author
- Lambirth, Kevin
- Date Created
- 2015
- Subjects--Topical
- Molecular biology, Biology, Bioinformatics
- Description
- The seeds of the common soybean (Glycine max) produce and store large amounts of protein, making them an appealing bioreactor for producing valuable recombinant proteins at high levels. However, the effects of accumulating recombinant protein at h...
- Title
- Regulation of Myosin IIIa Motor/Kinase Activity
- Author
- Moore, Judy
- Date Created
- 2009
- Subjects--Topical
- Biochemistry, Neurosciences, Cytology
- Description
- Myosin IIIa, a motor protein that localizes to actin-rich regions of photoreceptors and to stereocilia of inner ear hair cells, is associated with the hearing process in vertebrates and with phototransduction for invertebrates. It contains a large...
- Title
- Systematic Analysis of Antibiotic Resistance Genes (ARGs) in Water and Environmental System
- Author
- Park, Sol
- Date Created
- 2021
- Subjects--Topical
- Environmental engineering, Bioinformatics, Water resources development--Management
- Description
- The global research community is aware of the prevalence and ubiquity of antibiotic resistant genes (ARGs) which is increasing over time due to human activities (Allen et al. 2010; Baquero, Martínez, and Cantón 2008; Bergeron et al. 2016; Di Cesar...
- Title
- The Microbiota Multiverse: From Gut to Brain and Beyond
- Author
- Brown, Matthew
- Date Created
- 2019
- Subjects--Topical
- Microbiology, Bioinformatics
- Description
- This work explores the microbiomes of diverse biological contexts with various stakeholders and collaborators. It consists of six objectives: the first two relate to interaction between the gut microbiome and host health, the second two investigat...
- Title
- The effect of structure in short regions of DNA on measurements on short-oligonucleotide microarray and Ion Torrent PGM sequencing platforms
- Author
- Khoshnevis, Saeed
- Date Created
- 2013
- Subjects--Topical
- Bioinformatics
- Description
- Single-stranded DNA in solution has been studied by biophysicists for many years, as complex structures, both stable and dynamic, form under normal experimental conditions. Stable intra-strand formations affect enzymatic technical processes such a...
- Title
- The influence of wastewater treatment on community dynamics among antibiotic-resistant bacteria during treatment, stream release, and biosolids land application.
- Author
- Sorgen, Alicia
- Date Created
- 2020
- Subjects--Topical
- Microbiology, Bioinformatics, Ecology
- Description
- Wastewater treatment plants (WWTP) are a key link between anthropogenic activity and the environment, facilitating the development and horizontal transfer of antibiotic resistance among populations of commensal environmental microorganisms and cli...
- Title
- UV-Based Advanced Oxidation Processes and Nanoscale Antimicrobials for Antibiotic Resistance Mitigation
- Author
- Sorinolu, Adeola
- Date Created
- 2022
- Subjects--Topical
- Environmental engineering, Nanoscience, Microbiology
- Description
- Antibiotic resistance (AR) is an ongoing pandemic that is unnoticed by many. AR is a global public health issue that challenges therapeutic potential against pathogens of humans and animals. Predictably, the environment has been implicated in the ...