- Fodor, Anthony (x)
- Bioinformatics (x)
- Search results
Search results
- Title
- Comparative analysis of Nitrosococcus genomes; isolation, physiological and genomic characterization of the new ammonia-oxidizing species Nitrosococcus wardiae, strain D1FHST; and molecular studies towards a better understanding of ammonia-dependent chemolithotrophy
- Author
- Wang, Lin
- Date Created
- 2016
- Subjects--Topical
- Molecular biology, Biology, Genetics
- Description
- Obligate aerobic chemolithoautotrophic ammonia-oxidzing bacteria (AOB) derive energy and reductant needed for growth solely from the oxidation of ammonia to nitrite thereby facilitating the process of nitritation. A strain of an ammonia-oxidizing ...
- Title
- DATA ANALYSIS WORKFLOW FOR GAS CHROMATOGRAPHY MASS SPECTROMETRY-BASED METABOLOMICS STUDIES
- Author
- Ni, Yan
- Date Created
- 2014
- Subjects--Topical
- Bioinformatics
- Description
- Metabolomics has emerged as an integral part of systems biology research that attempts to comprehensively study low molecular weight organic and inorganic metabolites under certain conditions within a biological system. Technological advances in t...
- Title
- Development of Structural Informatics Method For Binding Peptides
- Author
- Patterson, John
- Date Created
- 2023
- Subjects--Topical
- Bioinformatics
- Description
- In the continuous pursuit of advanced therapeutics, the field of bioinformatics hasinnovated tools that allow unprecedented control over the proteome, profoundly shaping our understanding and manipulation of biological domains. Computational appro...
- Title
- ESSENTIAL DYNAMICS OF PROTEINS USING GEOMETRICAL SIMULATIONS AND SUBSPACE ANALYSIS
- Author
- David, Charles
- Date Created
- 2012
- Subjects--Topical
- Physics, Bioinformatics, Biophysics
- Description
- Essential dynamics is the application of principal component analysis to a dynamic trajectory derived from a simulation protocol in order to extract biologically relevant information contained in the high dimensional data. In this work, we apply t...
- Title
- Evolution and dynamics of transcriptional regulation in bacteria
- Author
- Li, Shan
- Date Created
- 2013
- Subjects--Topical
- Computer science, Statistics, Bioinformatics
- Description
- Although transcription is one of the most important biological functions of cells, our understanding of its regulation is still limited. In this dissertation, we have studied the transcriptional regulation in prokaryotes in three aspects. First, w...
- Title
- IDENTIFICATION OF EPITHELIAL OVARIAN TUMOR SPECIFIC APTAMERS THAT BIND AND INTERNALIZE INTO TARGET CELLS
- Author
- Benedetto, Gregory
- Date Created
- 2015
- Subjects--Topical
- Chemistry, Biology
- Description
- New clinical tools that aid in the early diagnosis of ovarian malignancies will significantly help reduce mortality and improve current long-term survival rates. The objective of the work presented here was to identify ovarian tumor specific singl...
- Title
- IMPROVEMENTS IN MICROBE RECOVERY AND DETECTION IN WATER SAMPLES: MULTIPLE APPROACHES TO METHOD OPTIMIZATION
- Author
- Kimble, Gina
- Date Created
- 2015
- Subjects--Topical
- Environmental engineering, Environmental sciences
- Description
- The accurate recovery and detection of microbes from water samples is important for the protection of public health. However, not all microbes behave similarly, not all water samples have comparable physical properties, and the constituents presen...
- Title
- Long-term study of changes in microbiota in a Cystic Fibrosis patient
- Author
- Stokell, Joshua
- Date Created
- 2013
- Subjects--Topical
- Biology, Microbiology
- Description
- Application of culture-independent techniques have revealed the presence of more types of bacteria than were previously thought, which led to the current description of Cystic Fibrosis (CF) being a polymicrobial disease. We know this polymicrobial...
- Title
- Microarray tools and analysis methods to better characterize biological networks
- Author
- Overall, Christopher
- Date Created
- 2012
- Subjects--Topical
- Bioinformatics
- Description
- To accurately model a biological system (e.g. cell), we first need to characterize each of its distinct networks. While omics data has given us unprecedented insight into the structure and dynamics of these networks, the associated analysis routin...
- Title
- Off-pump coronary artery bypass graft vs. on-pump coronary artery bypass graft surgery: What matters - procedure volume or specificity/specialization?
- Author
- Tsulukidze, Maka
- Date Created
- 2012
- Subjects--Topical
- Social sciences--Research
- Description
- Context: Existing research has associated higher provider volume with a lower rate of adverse patient outcomes after coronary artery bypass graft (CABG). However, the relationship between surgical procedural volume and specialization and clinical ...
- Title
- RECIPROCAL REGULATION OF MYC AND MICRORNA MIR-308 DURING DROSOPHILA EMBRYOGENESIS
- Author
- Daneshvar, Kaveh
- Date Created
- 2012
- Subjects--Topical
- Molecular biology, Biology, Genetics
- Description
- Myc is a conserved transcription factor with a role in the regulation of genes that are involved in growth and development. The abundance of Myc protein in the cells must be exquisitely controlled to avoid growth abnormalities caused by too much o...
- Title
- Studies on the relationships between oligonucleotide probe properties and hybridization signal intensities
- Author
- Gharaibeh, Raad
- Date Created
- 2009
- Subjects--Topical
- Computer science, Statistics, Bioinformatics
- Description
- Microarray technology is a commonly used tool in biomedical research for assessing global gene expression, surveying DNA sequence variations, and studying alternative gene splicing. Given the wide range of applications of this technology, comprehe...
- Title
- THE EFFECT OF TARGET SECONDARY STRUCTURE ON MICROARRAY DATA QUALITY
- Author
- Ratushna, Vladyslava
- Date Created
- 2010
- Subjects--Topical
- Bioinformatics, Biophysics
- Description
- DNA microarrays have become an invaluable high throughput biotechnology method, which allows a parallel investigation of thousands of cellular events in a single experiment. The principle behind the technology is very simple: fluorescently labeled...
- Title
- The influence of wastewater treatment on community dynamics among antibiotic-resistant bacteria during treatment, stream release, and biosolids land application.
- Author
- Sorgen, Alicia
- Date Created
- 2020
- Subjects--Topical
- Microbiology, Bioinformatics, Ecology
- Description
- Wastewater treatment plants (WWTP) are a key link between anthropogenic activity and the environment, facilitating the development and horizontal transfer of antibiotic resistance among populations of commensal environmental microorganisms and cli...
- Title
- Topoisomerase II Inhibitors Induce an Illegitimate Genome Rearrangement Common in Infant Leukemia
- Author
- Bariar, Bhawana
- Date Created
- 2013
- Subjects--Topical
- Molecular biology
- Description
- Infant acute leukemias account for ~30% of all malignancy seen in childhood across the Western world. They are aggressive and characterized by rapid onset shortly after birth. The majority of these have rearrangements involving the MLL (mixed line...