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Abrogating the oncogenic signaling associated with tumor MUC1 in Pancreatic Ductal Adenocarcinoma
Title
Abrogating the oncogenic signaling associated with tumor MUC1 in Pancreatic Ductal Adenocarcinoma
Author
Bose, Mukulika
Date Created
2022
Subjects--Topical
Molecular biology, Biochemistry, Oncology
Description
Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal human cancers. The incidence rate of PDA nearly matches its mortality rate and the best treatment till date is surgical resection for which only 25\% are eligible. Tumor recurrence a...
Dry Preservation of Germinal Vesicles: Development of a New Formulation to Preserve DNA Integrity Under Adverse Environmental Conditions
Title
Dry Preservation of Germinal Vesicles: Development of a New Formulation to Preserve DNA Integrity Under Adverse Environmental Conditions
Author
Orozco Cabral, Joseph
Date Created
2022
Subjects--Topical
Biology, Bioengineering
Description
Advances in the cryopreservation of genetic material has revolutionized human reproductive medicine and animal conservation efforts. Despite many successes, oocytes have been more challenging to cryopreserve than sperm. Their large size makes it d...
The Determination of Temperature-dependent CPA Diffusion Properties in Feline Testicular Tissue
Title
The Determination of Temperature-dependent CPA Diffusion Properties in Feline Testicular Tissue
Author
Kirkland, Kaitlyn
Date Created
2022
Subjects--Topical
Biomedical engineering
Description
Fertility preservation would benefit young males who must undergo treatments that can result in sterilization, such as radiation treatments for cancer. This can be achieved by removing some testicular tissue before treatment and putting it into fr...
The Local Dynamics of Basement Membrane Breaching During Cancer Cell Invasion
Title
The Local Dynamics of Basement Membrane Breaching During Cancer Cell Invasion
Author
Nazari, Shayan
Date Created
2022
Subjects--Topical
Biology
Description
Solid tumor metastasis is the leading cause of cancer-related mortality. Cancer invasion through the confining basement membrane (BM) is the initial step in tumor dissemination and metastasis, and it represents a key diagnostic feature of cancer. ...