Search results | J. Murrey Atkins Library

Title: Abrogating the oncogenic signaling associated with tumor MUC1 in Pancreatic Ductal Adenocarcinoma
Author: Bose, Mukulika
Date Created: 2022
Subjects--Topical: Molecular biology, Biochemistry, Oncology
Description: Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal human cancers. The incidence rate of PDA nearly matches its mortality rate and the best treatment till date is surgical resection for which only 25\% are eligible. Tumor recurrence a...

Title: Additive Manufacturing of 3D Printed SiC Composites: Strengthening and Densification through Surface Modification and Use of Mineral Binders
Author: Chandrasekaran, Sujithra
Date Created: 2023
Subjects--Topical: Engineering, Materials science, Mechanical engineering
Description: Manufacturing of dense SiC composites counts mainly on the thermal oxidation of the carbide into silica. The irregularity of the silica layer and its limited thickness weaken the bond between particles and diminish the good thermo-mechanical prope...

Title: Bioactive ceramic coating on orthopedic implants for enhanced bone tissue integration
Author: Aniket, .
Date Created: 2012
Subjects--Topical: Materials science, Nanoscience, Biomedical engineering
Description: Tissue integration between bone and orthopedic implant is essential for implant fixation and longevity. An immunological response leads to fibrous encapsulation of metallic implants leading to implant instability and failure. Bioactive ceramics ha...

Title: Development of injectable bioceramic drug delivery system for solid tumor treatment
Author: Haig, James
Date Created: 2017
Subjects--Topical: Materials science, Engineering, Biomedical engineering
Description: According to the national cancer institute "In 2016, an estimated 1,685,210 new cases of cancer will be diagnosed in the United States and 595,690 people will die from the disease" and "The number of people living beyond a cancer diagnosis reached...

Title: EFFECT OF BIOCERAMIC FUNCTIONAL GROUPS ON DRUG BINDING AND RELEASE KINETICS
Author: Trujillo, Christopher
Date Created: 2015
Subjects--Topical: Materials science, Engineering, Biomedical engineering
Description: Bioceramics have been studied extensively as drug delivery systems (DDS). Those studies have aimed to tailor the drug binding and release kinetics to successfully treat infections and other diseases. This research suggests that the drug binding an...

Title: ENGINEERING BIOCERAMIC MICROSTRUCTURE FOR CUSTOMIZED DRUG DELIVERY
Author: Pacheco, Hernando
Date Created: 2013
Subjects--Topical: Engineering, Biomedical engineering
Description: One of the most efficient approaches to treat cancer and infection is to use biomaterials as a drug delivery system (DDS). The goal is for the material to provide a sustained release of therapeutic drug dose locally to target the ill tissue withou...

Title: Effects of External Biofeedback on Biomechanics and Ankle Joint Health in Individuals With Chronic Ankle Instability
Author: Torp, Danielle
Date Created: 2021
Subjects--Topical: Kinesiology
Description: Individuals with chronic ankle instability (CAI) often demonstrate abnormal biomechanical patterns which may be associated with the onset of posttraumatic osteoarthritis (PTOA). There is a lack of interventions capable of changing gait impairments...

Title: Enhanced Thermal Imaging a Novel Imaging Technique for Monitoring Re-Perfusion Post-Operatively
Author: McGinnis, Cobey
Date Created: 2023
Subjects--Topical: Optics, Biomedical engineering, Physics
Description: We are developing a real-time infrared imaging technique, Enhanced Thermal Imaging(ETI), that can detect blood vessels embedded in tissue and assess tissue perfusion. ETI is a combination of standard thermal imaging (8 - 10 μm) and selective heati...

Title: FUNCTIONAL NUCLEIC ACID NANOPARTICLES AND THEIR DELIVERY
Author: Ke, Weina
Date Created: 2020
Subjects--Topical: Biochemistry, Cytology
Description: Nucleic acid biopolymers are essential to all living organisms. The chemical makeup of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) consist of sequences of only four monomers. However, they transmit and express genetic information for va...

Title: Interaction between hydrogen sulfide and endothelin-1 in hepatic perfusion and mitochondrial dynamics in endotoxemia
Author: Pennington, Samantha
Date Created: 2018
Subjects--Topical: Physiology, Cytology
Description: A mismatch between oxygen supply and metabolic tissue demand leads to the development of hypoxia, which contributes to hepatic dysfunction and liver injury during sepsis. Recent evidence shows that hepatic H2S levels are increased during sepsis an...

Title: MODELING CRASH RISK DUE TO TRAFFIC RULE VIOLATIONS FOR EDUCATION, ENFORCEMENT AND ENGINEERING COUNTERMEASURES
Author: Penmetsa, Praveena
Date Created: 2017
Subjects--Topical: Civil engineering, Transportation
Description: With 1.3 million deaths, motor vehicle crashes contributed to 2.2% of the total deaths in the world during 2012. Traffic rule violations are the major reason for the occurrence of crashes and fatalities world-wide. Education, enforcement and engin...

Title: RED FLUORESCENCE IN BOVINE SERUM ALBUMIN – GOLD COMPLEXES
Author: Dixon, Jacob
Date Created: 2019
Subjects--Topical: Optics, Physics
Description: Bovine serum albumin (BSA)-gold (Au) complexes have been studied in great detail due to their unique red fluorescent (λem = 640 nm) properties, since being initially described by Xie et al. (J. Am. Chem. Soc. 2009, 131, 888-889) as a Au25 nanoclus...

Title: ROLE OF AQUAPORINS DURING HEPATOCELLULAR CARCINOMA INITIATION AND PROGRESSION
Author: Mattocks, Matthew
Date Created: 2010
Subjects--Topical: Molecular biology, Cytology, Oncology
Description: Aquaporins (AQPs) are ubiquitously expressed proteinaceous water channels involved in numerous physiological processes including bile production and apoptosis. Aquaporins 8 and 9 are expressed in hepatocytes, and are down regulated in a rat model ...

Title: Role of Nonmuscle Myosin II in Hepatic Stellate Cell Activation
Author: Moore, Cathy
Date Created: 2009
Subjects--Topical: Molecular biology
Description: The hepatic stellate cell (HSC) plays a pivotal role in the development of hepatic fibrosis. Regulation of liver microcirculation is a complex system where blood flow is under systemic and sinusoidal control. Upon a fibrogenic stimulus, quiescent ...

Title: SELECTIVE HEATING OF VASCULAR STRUCTURES TO CREATE CONTRAST IN MEDICAL MID-IR IMAGES
Author: Case, Jason
Date Created: 2015
Subjects--Topical: Optics, Diagnostic imaging
Description: The goal of this study is to develop an enhanced mid-IR imaging modality for mapping vascular structures. This imaging technique is intended for real-time use by medical professionals during surgical procedures such as tumor removal and vascular m...

Title: SINGLE-STEP, REDUCED SHEAR, MICROFLUIDIC EXTRUSION OF BLOOD BRAIN BARRIER
Author: Wetzel, Isaac
Date Created: 2019
Subjects--Topical: Biomedical engineering
Description: Three-dimensional (3D) bioprinting of living structures with cell-laden biomaterials has been achieved in vitro, however, central nervous system tissues have been limited by the low viability printing of cerebral vessels, using conventional printi...

Title: TRANSCRIPTIONAL REGULATION OF GENES ASSOCIATED WITH DRUG RESISTANCE AND GROWTH OF PANCREATIC CANCER CELLS BY MUCIN 1
Author: Nath, Sritama
Date Created: 2013
Subjects--Topical: Molecular biology, Cytology, Oncology
Description: Pancreatic ductal adenocarcinoma (PDA) is the 4th leading cause of cancer-related deaths in the US. An understanding of the molecular pathogenesis of PDA is of utmost importance to be able to improve the current or design new targeted therapies fo...

Title: The Determination of Temperature-dependent CPA Diffusion Properties in Feline Testicular Tissue
Author: Kirkland, Kaitlyn
Date Created: 2022
Subjects--Topical: Biomedical engineering
Description: Fertility preservation would benefit young males who must undergo treatments that can result in sterilization, such as radiation treatments for cancer. This can be achieved by removing some testicular tissue before treatment and putting it into fr...