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Investigating Multidrug Resistance in Escherichia coli with Phylogenetics and Machine Learning
Title
Investigating Multidrug Resistance in Escherichia coli with Phylogenetics and Machine Learning
Author
Brown, David
Date Created
2023
Subjects--Topical
Bioinformatics, Biometry, Computer science
Description
The next pandemic is already underway in the proliferation of antimicrobial resistance(AMR) genes that reduce the effectiveness of therapeutics. The lessened potency of these current drugs results in increased economic costs, higher public health ...
On Compositionally Aware and Naïve Approaches to Normalization of 16S Microbiome Data
Title
On Compositionally Aware and Naïve Approaches to Normalization of 16S Microbiome Data
Author
Yerke, Aaron
Date Created
2022
Subjects--Topical
Bioinformatics
Description
Compositional data refers to any data that represents parts of a whole, and DNA sequencing data is compositional in nature. This is due to the constraint on our current sequencing technologies that allow us to record a sample of the sequences rath...
On Whole Genome Classifier Perforamnce in Relation to 16S Classifiers
Title
On Whole Genome Classifier Perforamnce in Relation to 16S Classifiers
Author
Johnson, James
Date Created
2022
Subjects--Topical
Bioinformatics
Description
There is little consensus in the literature as to which approach for classification of Whole Genome Shotgun (WGS) sequences is most accurate unlike 16S classifiers that have had more time to mature. In this dissertation, two of the most popular cl...