I-motifs are intercalated cytosine quadruplexes discovered in 1993, but they weren’t shown to exist in the cell nucleus until 2018. While their biological role has yet to be fully elucidated, they have been implicated in regulating expression of s...
Bacterial cell surface glycans mediate pathogenic and symbiotic interactions with hosts and other organisms. The implications of bacterial glycans in human health have made them attractive targets in drug design for antibiotics, antibacterial vacc...
Metabolomics has emerged as an integral part of systems biology research that attempts to comprehensively study low molecular weight organic and inorganic metabolites under certain conditions within a biological system. Technological advances in t...
Malaria retains its position as one of the most highly transferable diseases throughout the world today, with current efforts focused on controlling its spread. A sensitive, asymptomatic-stage detection method is needed to diagnose malaria before ...
This thesis describes the synthesis and characterization of novel cellulose graft copolymers that are used for the purification of drinking water. These nanomaterials function as bottle-brush anion-exchange resins with repeating quaternary ammoniu...
Microarray technology is a commonly used tool in biomedical research for assessing global gene expression, surveying DNA sequence variations, and studying alternative gene splicing. Given the wide range of applications of this technology, comprehe...
Bordetella pertussis is a gram-negative bacterium that is the causative agent of whooping cough, a highly contagious disease that can be fatal in very young children. The outer membrane of the bacteria consists mainly of lipolysaccharide (LPS), an...