Search results
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Title
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A STRUCTURAL AND FUNCTIONAL ANALYSIS OF NEMATOSTELLA VECTENSIS MAJOR INTRINSIC PROTEINS
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Author
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Taylor, Jonathon
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Date Created
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2020
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Subjects--Topical
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Biology, Cytology, Evolutionary developmental biology
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Description
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There is currently a major gap in understanding the physiological processes of tissue grade animals from early diverging phyla, particularly within the context of the molecular mechanisms in response to osmotic variation. A key protein family esse...
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Title
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Development of Silica Based Nanoparticles for Multimodal Therapeutic Delivery
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Author
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Vadarevu, Hemapriyadarshini
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Date Created
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2022
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Subjects--Topical
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Nanoscience
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Description
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Chronic diseases like cancer are characterized by complex interactions between multiple pathways leading to treatment resistance and invasiveness. Repeated cycles of cytotoxic monotherapies are susceptible to drug resistance induced by the upregul...
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Title
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Dissecting functional differences in Hsp70 isoforms in nematostella vectensis
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Author
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Waller, Shawn
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Date Created
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2018
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Subjects--Topical
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Molecular biology
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Description
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Heat shock protein 70s (Hsp70s) are a highly conserved class of molecular chaperones that are involved in cellular processes in all organisms such as stress response, homeostatic maintenance, and cell cycle progression. The organism Nematostella v...
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Title
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Synthetic Approaches to Novel (Oxa)cages From a Polycyclic Hydrocarbon Framework
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Author
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Faussett, Matthew
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Date Created
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2022
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Subjects--Topical
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Chemistry, Organic
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Description
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Organic cage chemistry, an incredibly diverse sect of organic synthesis, has alwaysintrigued chemists to push the limits of synthetic knowledge, to explore novel structural elements, and to understand unique reactivity patterns. Organic cage compo...
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Title
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Understanding Chaperone interactions in disease
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Author
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Nitika
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Date Created
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2021
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Subjects--Topical
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Molecular biology, Biochemistry, Cytology
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Description
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The correct folding of proteins after synthesis and stress-promoted denaturation is critical for cell viability in all organisms. The Hsp70 molecular chaperone is a key player in proteostasis, deciding which proteins are foldable and which are too...