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Newly described cytosolic pattern recognition receptors mediate inflammatory glial responses to neurotropic viruses
Title
Newly described cytosolic pattern recognition receptors mediate inflammatory glial responses to neurotropic viruses
Author
Furr, Samantha
Date Created
2012
Subjects--Topical
Immunology, Biology
Description
The rapid onset of potentially lethal neuroinflammation is a defining feature of viral encephalitis. Glial cells are ideally positioned to respond to invading pathogens of the central nervous system (CNS) and produce key inflammatory mediators fol...
ROLE OF THE NOVEL DNA SENSORS cGAS, IFI16, AND ZBP1, DURING VIRAL INFECTIONS IN GLIA
Title
ROLE OF THE NOVEL DNA SENSORS cGAS, IFI16, AND ZBP1, DURING VIRAL INFECTIONS IN GLIA
Author
Jeffries, Austin
Date Created
2020
Subjects--Topical
Immunology, Virology, Neurosciences
Description
Viral central nervous system (CNS) infections can lead to life threatening encephalitis and long-term neurological deficits in survivors. Resident CNS cell types, such as astrocytes and microglia, are known to produce key inflammatory and antivira...
THE ROLE OF MUC1 IN REGULATION AND PROGRESSION OF CANCER
Title
THE ROLE OF MUC1 IN REGULATION AND PROGRESSION OF CANCER
Author
Sahraeimanouchehrabadi, Mahnaz
Date Created
2011
Subjects--Topical
Immunology, Biology, Oncology
Description
MUC1 is a heavily glycosylated transmembrane glycoprotein which is overexpressed and aberrantly glycosylated in most human carcinomas. MUC1 contains a large tandem repeat, a short transmembrane, and a small cytoplasmic tail. Both tandem repeat and...