- Lo, Eugenia (x)
- Blackburn, Kayla (x)
- Search results
Search results
- Title
- Frequent expansion of Plasmodium vivax Duffy Binding Protein in Ethiopia and its epidemiological significance
- Author
- Janies, Daniel, Lo, Eugenia, Kepple, Daniel
- Date Created
- 2019
- Subjects--Topical
- Communicable diseases, Malaria
- Description
- Plasmodium vivax invasion of human erythrocytes depends on the Duffy Binding Protein (PvDBP) which interacts with the Duffy antigen. PvDBP copy number has been recently shown to vary between P. vivax isolates in Sub-Saharan Africa. However, the ex...
- Title
- Gene polymorphisms among Plasmodium vivax geographical isolates and the potential as new biomarkers for gametocyte detection
- Author
- Janies, Daniel, Lo, Eugenia, Ford, Anthony
- Date Created
- 2022
- Subjects--Topical
- Genomics, Biology
- Description
- The unique biological features of Plasmodium vivax not only make it difficult to control but also to eliminate. For the transmission of the malaria parasite from infected human to the vector, gametocytes play a major role. The transmission potenti...
- Title
- Implementing landscape genetics in molecular epidemiology to determine drivers of vector‐borne disease : a malaria case study
- Author
- Lo, Eugenia, Janies, Daneil, Hubbard, Alfred, Afrane, Yaw
- Date Created
- 2023
- Subjects--Topical
- Malaria, Protozoan diseases
- Description
- This study employs landscape genetics to investigate the environmental drivers of a deadly vector-borne disease, malaria caused by Plasmodium falciparum, in a more spatially comprehensive manner than any previous work. With 1804 samples from 44 si...
- Title
- Patch dynamics modeling framework from pathogens' perspective : Unified and standardized approach for complicated epidemic systems
- Author
- Janies, Daniel, Chen, Shi, Lo, Eugenia, Dulin, Michael
- Date Created
- 2020
- Subjects--Topical
- Communicable diseases, Biology
- Description
- Mathematical models are powerful tools to investigate, simulate, and evaluate potential interventions for infectious diseases dynamics. Much effort has focused on the Susceptible-Infected-Recovered (SIR)-type compartment models. These models consi...
- Title
- Selection and utility of single nucleotide polymorphism markers to reveal fine-scale population structure in human malaria parasite Plasmodium falciparum
- Author
- Janies, Daniel, Lo, Eugenia, Ford, Anthony
- Date Created
- 2018
- Subjects--Topical
- Communicable diseases, Malaria
- Description
- Single nucleotide polymorphisms (SNPs) have been shown to be useful in revealing population structure with continental-and regional-scale samples. In epidemiological study, a careful selection of SNPs to track disease spread in local communities w...
- Title
- Submicroscopic infection and G6PD deficiency in malaria patients
- Author
- Witherspoon, Logan, Witherspoon, Logan, Kepple, Daniel, Lo, Eugenia, Abagero, Beka
- Date Created
- 2022, 2022, 2022
- Subjects--Topical
- Malaria, Public health
- Description
- Plasmodium vivax malaria is a neglected tropical disease, despite being more geographically widespread than any other form of malaria. Glucose-6-phosphate dehydrogenase (G6PD) is a cytosolic enzyme with a vital role for the integrity and functioni...
- Title
- Whole genome sequencing of Plasmodium vivax isolates reveals frequent sequence and structural polymorphisms in erythrocyte binding genes
- Author
- Janies, Daniel, Lo, Eugenia, Ford, Anthony, Kepple, Daniel
- Date Created
- 2020
- Subjects--Topical
- Communicable diseases, Malaria
- Description
- Plasmodium vivax malaria is much less common in Africa than the rest of the world because the parasite relies primarily on the Duffy antigen/chemokine receptor (DARC) to invade human erythrocytes, and the majority of Africans are Duffy negative. R...