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Bis(bipyridyl)silicon(IV) Diols as Potential Dual Hydrogen Bond Donors for Catalysis
Title
Bis(bipyridyl)silicon(IV) Diols as Potential Dual Hydrogen Bond Donors for Catalysis
Author
Waters, Crystal
Date Created
2016
Subjects--Topical
Chemistry
Description
Hydrogen bond donors (HBDs) have been explored as potential catalysts for the 1,4-conjugate addition and Diels-Alder reactions. HBD catalysis, which relies on Brønsted acid catalytic sites, is being explored as an oxygen and moisture stable altern...
ELUCIDATING THE MOLECULAR BASIS OF INHIBITION OF ENZYMES ESSENTIAL FOR BATERIALVIRULENCE: THE ACTIVITY OF THREE GLYCOSYLTRANSFERASES AND A POTENTIAL DRUG TARGET, UNDECAPRENYL PYROPHOSPHATE SYNTHASE
Title
ELUCIDATING THE MOLECULAR BASIS OF INHIBITION OF ENZYMES ESSENTIAL FOR BATERIALVIRULENCE: THE ACTIVITY OF THREE GLYCOSYLTRANSFERASES AND A POTENTIAL DRUG TARGET, UNDECAPRENYL PYROPHOSPHATE SYNTHASE
Author
Okwei, Elleansar
Date Created
2016
Subjects--Topical
Chemistry, Biology, Biochemistry
Description
The fight against bacterial infection is one of the most important branches of modern medicine. Due to the emergence of strains of antibiotic-resistant bacteria, researchers have been presented with complex challenges in an effort to combat these ...
Exceptional New Reagents for Bioconjugation
Title
Exceptional New Reagents for Bioconjugation
Author
Garmon, Corey
Date Created
2016
Subjects--Topical
Chemistry, Biochemistry
Description
At about the turn of this century the term "click" chemistry came into the common vernacular amongst chemists. "Click" is used to describe reactions that are "spring-loaded" and proceed well in a predictable manner, with no offensive byproduct and...
Folate Receptor-Specific, Redox-Responsive Mesoporous Silica Nanoparticles for the Simultaneous Delivery of Cisplatin and Gemcitabine to Treat Cancer
Title
Folate Receptor-Specific, Redox-Responsive Mesoporous Silica Nanoparticles for the Simultaneous Delivery of Cisplatin and Gemcitabine to Treat Cancer
Author
Fink, Eric
Date Created
2016
Subjects--Topical
Materials science, Chemistry, Biochemistry
Description
Nanoparticles are an innovative platform for cancer treatment that reduces systemic toxicity and allows for active targeting of tumor sites to enhance the therapeutic efficacy. Mesoporous silica nanoparticles (MSNs) have emerged as an attractive d...
Investigations into the Reactivity and Structure of Organocuprates
Title
Investigations into the Reactivity and Structure of Organocuprates
Author
Morse, Jared
Date Created
2016
Subjects--Topical
Chemistry
Description
While organocuprate reagents have been a staple in synthetic organic chemistry in the formation of carbon-carbon bonds, there has been a dearth of investigations into its use in forming carbon-heteroatom bonds. In previous cases of complexes betwe...
Synthesis and characterization of single-walled carbon nanotubes for use in water purification
Title
Synthesis and characterization of single-walled carbon nanotubes for use in water purification
Author
Johnson, Billy
Date Created
2016
Subjects--Topical
Materials science, Nanoscience, Chemistry
Description
As human health concerns over disinfection byproducts (DBPs) in drinking water increase, so does the need to development new materials that remove them rapidly and at high-efficiency. Ion exchange (IEX) is an effective method for the removal of na...
Synthesis, Reactivity, and Applications of Benzimidazole Thiones and Selones
Title
Synthesis, Reactivity, and Applications of Benzimidazole Thiones and Selones
Author
Hernandez, Lizeth
Date Created
2016
Subjects--Topical
Chemistry
Description
Benzimidazole-2-thiols and their transition metal complexes have been the focus of intense research due to their potential applications in bioinorganic and organometallic chemistry. Within this field of research, the synthesis and reactivity of be...