Search results
- Title
- Characterization of the Colanic Acid Biosynthesis Pathway with a Fluorescent Bactoprenyl Monophosphate Analogue
- Author
- Scott, Phillip
- Date Created
- 2015
- Subjects--Topical
- Biochemistry
- Description
- When introduced to harsh conditions such as low pH, pathogenic Escherichia coli can secrete colanic acid, an exopolysaccharide that completely engulfs the organism, to establish a protective barrier between the organism and the acidic environment....
- Title
- Cholera Toxin Subunit B-Mediated Intracellular Trafficking of Mesoporous Silica Nanoparticles Toward the Endoplasmic Reticulum
- Author
- Walker, William
- Date Created
- 2015
- Subjects--Topical
- Materials science, Nanoscience, Biomedical engineering
- Description
- In recent decades, pharmaceutical research has led to the development of numerous treatments for human disease. Nanoscale delivery systems have the potential to maximize therapeutic outcomes by enabling target specific delivery of these therapeuti...
- Title
- Design, Synthesis, Characterization and Simulation of Polyhedral Oligomeric Silsesquioxane Porphyrin Molecules to Fabricate Self-Assembled Nanoparticles and Their Use for Photodynamic Therapy
- Author
- Loman-Cortes, Paula
- Date Created
- 2021
- Subjects--Topical
- Nanoscience
- Description
- PAULA LOMAN-CORTES. Design, Synthesis, Characterization and Simulation of Polyhedral Oligomeric Silsesquioxane Porphyrin Molecules to Fabricate Self-Assembled Nanoparticles and Their Use for Photodynamic Therapy. (Under the direction of DR JUAN L ...
- Title
- FUNCTIONAL NUCLEIC ACID NANOPARTICLES AND THEIR DELIVERY
- Author
- Ke, Weina
- Date Created
- 2020
- Subjects--Topical
- Biochemistry, Cytology
- Description
- Nucleic acid biopolymers are essential to all living organisms. The chemical makeup of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) consist of sequences of only four monomers. However, they transmit and express genetic information for va...
- Title
- FUNCTIONALIZATION AND CHARACTERIZATION OF NOVEL COORDINATION COMPLEXES FOR USE IN SUPERCAPACITORS
- Author
- Zuczek, Justin
- Date Created
- 2018
- Subjects--Topical
- Materials science, Power resources
- Description
- As society begins to move away from fossil fuel consumption and the harmful effects they entail, renewable energy sources have been studied extensively over the past decades. One obstacle with renewable energy is the ability to cheaply store it du...
- Title
- HEXACOORDINATE SILICON COMPLEXES FOR ELECTRONIC DEVICES
- Author
- Kochegra, Margaret
- Date Created
- 2020
- Subjects--Topical
- Nanoscience
- Description
- Organic electronics such as organic light emitting diodes, organic photovoltaics, organic field effect transistors begin to replace classically used technology. This is due to their tailorability, possibility of smaller and flexible devices, and n...
- Title
- INCORPORATION OF FLUORESCENT ANALOGUES IN ISOPRENOID PATHWAYS IN ESCHERICHIA COLI
- Author
- George, Chelsea
- Date Created
- 2018
- Subjects--Topical
- Biochemistry
- Description
- Bacterial glycans and glycoconjugates have wide diversity compared to their eukaryotic counterparts. While methods have been developed to monitor and track glycans in eukaryotic systems with some success, there are limited methods with which to do...
- Title
- INVESTIGATION OF THE CURRENT TRANSPORT MECHANISMS IN FIRE THROUGH DIELECTRIC CONTACT (FTDC) TO SILICON SOLAR CELLS BY SPECTROSCOPIC ANALYSES
- Author
- Ren, Keming
- Date Created
- 2020
- Subjects--Topical
- Nanoscience
- Description
- This thesis work investigates the current transport mechanisms at the Si/gridline interface of the screen-printed commercial silicon (Si) solar cell with lowly doped emitter. The use of lightly doped emitter is one way to improve the efficiency of...
- Title
- Mass Spectrometric Protein Footprinting of Conformational Changes Induced by Chromatographic Surfaces
- Author
- Focke, Kimberly
- Date Created
- 2022
- Subjects--Topical
- Analytical chemistry, Biochemistry
- Description
- Reversed-phase liquid chromatography (RPLC) of intact proteins induces conformational changes due to the denaturing effects of both the hydrophobic stationary phase and the high-organic mobile phase, which can lead to poor recovery and badly disto...
- Title
- NUCLEIC ACID-DRIVEN QUANTUM DOT-BASED LATTICE FORMATIONS FOR BIOMEDICAL APPLICATIONS
- Author
- Roark, Brandon
- Date Created
- 2017
- Subjects--Topical
- Nanoscience, Nanotechnology, Biochemistry
- Description
- We present a versatile biosensing strategy that uses nucleic acids programmed to undergo an isothermal toehold mediated strand displacement in the presence of analyte. This rearrangement results in a double biotinylated duplex formation that induc...
- Title
- ORGANIZATION OF BIOMOLECULES IN A 3-DIMENSIONAL SPACE
- Author
- Sajja, Sameer
- Date Created
- 2019
- Subjects--Topical
- Nanotechnology, Biochemistry
- Description
- The human body operates using various stimuli-responsive mechanisms, dictating biological activity via reaction to external cues. Hydrogels are networked hydrophilic polymeric materials that offer the potential to recreate aqueous environments wit...
- Title
- ORGANIZATION OF BIOMOLECULES IN A 3-DIMENSIONAL SPACE
- Author
- Sajja, Sameer
- Date Created
- 2019
- Subjects--Topical
- Biochemistry
- Description
- The human body operates using various stimuli-responsive mechanisms, dictating biological activity via reaction to external cues. Hydrogels are networked hydrophilic polymeric materials that offer the potential to recreate aqueous environments wit...
- Title
- RNA Kissing Loop Library to expand RNA Fiber functionality and control cargo load for potential intracellular siRNA delivery.
- Author
- Shevchenko, Oleg
- Date Created
- 2020
- Subjects--Topical
- Nanoscience, Nanotechnology, Biochemistry
- Description
- A kissing loop (KL) is an RNA motif that among others may have a 180° geometry when derived from a viral genome. The KL interactions of this geometry consist of nine base pairs, six of which are interacting in complementary binding while three are...
- Title
- SYNTHESIS, CHARACTERIZATION, AND APPLICATION OF SILICA-BASED NANOPARTICULATE PLATFORMS FOR THE DELIVERY OF PHOTOSENSITIZERS IN THE USE OF PHOTODYNAMIC THERAPY FOR CANCER TREATMENT
- Author
- Lyles, Zachary
- Date Created
- 2018
- Subjects--Topical
- Nanoscience
- Description
- Triple negative breast cancer (TNBC) is a subtype of breast cancer which lacks expressions of hormonal receptors (ER/PR/HER2) and other meaningful targets. TNBC is characterized by intra-tumoral heterogeneities, high proliferative activity, poor p...
- Title
- Synthesis and Reactivity of Benzodiazepine-Derived Heterocyclic Thiones and Selones
- Author
- Clinkscales, Alexander
- Date Created
- 2021
- Subjects--Topical
- Chemistry, Inorganic, Chemistry, Organic, Analytical chemistry
- Description
- This thesis outlines the synthesis, characterization and coordination chemistry of new N-heterocylic benzodiazepine thione (NHT) and selone (NHSe) ligands. This new family of ligands, SBzDzArE (Ar = Xy, Mes, Dipp; E = S, Se), contain various bulky...
- Title
- Synthesis and Reactivity of N-Heterocyclic Chalcogenone Complexes of Copper and Silver
- Author
- Allen, Alexander
- Date Created
- 2018
- Subjects--Topical
- Chemistry, Inorganic, Chemistry, Organic, Analytical chemistry
- Description
- This presentation outlines the synthesis and characterization of several unusual two-coordinate copper(I) and silver(I) complexes supported by bulky N-heterocyclic thione (NHT) and selone (NHSe) ligands. More specifically, copper(I) complexes of t...
- Title
- Synthetic Approaches to Novel (Oxa)cages From a Polycyclic Hydrocarbon Framework
- Author
- Faussett, Matthew
- Date Created
- 2022
- Subjects--Topical
- Chemistry, Organic
- Description
- Organic cage chemistry, an incredibly diverse sect of organic synthesis, has alwaysintrigued chemists to push the limits of synthetic knowledge, to explore novel structural elements, and to understand unique reactivity patterns. Organic cage compo...