Search results
- Title
- A WATER-SOLUBLE COBALT SULFIDE SUPERATOM FOR FLOW BATTERY APPLICATIONS AND CRYSTALLINE FRAMEWORK SYNTHESIS
- Author
- Freeman, Matthew
- Date Created
- 2019
- Subjects--Topical
- Chemistry
- Description
- Metal sulfide clusters are attractive components for flow batteries owing to the abundance of their constituent atoms and their tunable size, solubility, and redox properties. We prepared an atomically precise cobalt sulfide cluster, Co6S8(PTA)6•4...
- Title
- Analysis and Development of Targeting Strategies for Bacterial Sugars
- Author
- Erickson, Katelyn
- Date Created
- 2018
- Subjects--Topical
- Chemistry, Biochemistry
- Description
- Bacterial cell surface exopolysaccharides aid in protecting microbes from the defense mechanisms of the host, and differ substantially in structure between species. Exploiting these structural differences would be advantageous to target certain ty...
- Title
- Bis(bipyridyl)silicon(IV) Diols as Potential Dual Hydrogen Bond Donors for Catalysis
- Author
- Waters, Crystal
- Date Created
- 2016
- Subjects--Topical
- Chemistry
- Description
- Hydrogen bond donors (HBDs) have been explored as potential catalysts for the 1,4-conjugate addition and Diels-Alder reactions. HBD catalysis, which relies on Brønsted acid catalytic sites, is being explored as an oxygen and moisture stable altern...
- Title
- Bis(bipyridyl)silicon(IV) compounds – synthesis, characterization, and catalytic properties.
- Author
- Maguylo, Christina
- Date Created
- 2015
- Subjects--Topical
- Chemistry, Chemistry, Inorganic
- Description
- A series of novel hexacoordinate bis-bipyridylsilicon(IV) complexes have been synthesized by reacting [Si(bipy)2I2]I2 with the appropriate alcohol or diol. Characterization was done and crystal structures have been obtained for the complexes: [Si(...
- Title
- Characterization of the Colanic Acid Biosynthesis Pathway with a Fluorescent Bactoprenyl Monophosphate Analogue
- Author
- Scott, Phillip
- Date Created
- 2015
- Subjects--Topical
- Biochemistry
- Description
- When introduced to harsh conditions such as low pH, pathogenic Escherichia coli can secrete colanic acid, an exopolysaccharide that completely engulfs the organism, to establish a protective barrier between the organism and the acidic environment....
- Title
- Chemical Tools for Biology
- Author
- Fessler, Adam
- Date Created
- 2017
- Subjects--Topical
- Chemistry
- Description
- Reagents for biotinylation that are innately water-soluble and can be tracked by both UV-vis spectroscopy and fluorescence (330nm/420nm) have been developed. These reagents are based on the isatoic anhydride platform, which gives rise to their val...
- Title
- Cholera Toxin Subunit B-Mediated Intracellular Trafficking of Mesoporous Silica Nanoparticles Toward the Endoplasmic Reticulum
- Author
- Walker, William
- Date Created
- 2015
- Subjects--Topical
- Materials science, Nanoscience, Biomedical engineering
- Description
- In recent decades, pharmaceutical research has led to the development of numerous treatments for human disease. Nanoscale delivery systems have the potential to maximize therapeutic outcomes by enabling target specific delivery of these therapeuti...
- Title
- Complex Glycan Synthesis in Bacteria
- Author
- Wallen, Timothy
- Date Created
- 2019
- Subjects--Topical
- Chemistry
- Description
- Glycans, which are assembled through a process known as glycosylation, are critical for creating biological structures important for the function and vitality of bacterial cells. In order to study the synthesis of glycans, enzymes and intermediate...
- Title
- Conditioning of Platinum Nanoparticle Catalysts for Improved Hydrogen Generation on P3HT:PCBM Bulk Heterojunction Photocathodes
- Author
- Ivins, Reynolds
- Date Created
- 2015
- Subjects--Topical
- Chemistry, Environmental engineering, Renewable energy sources
- Description
- This work aims to design, develop, and investigate the capacity of a metal catalyst-coated organic photoelectrode to produce molecular hydrogen when illuminated in acidic media. 3-5 nm platinum nanoparticles (PtNPs) were synthesized, treated to re...
- Title
- DESIGN, SYNTHESIS AND CHARACTERIZATION OF MULTIFUNCTIONAL REDOX-RESPONSIVE PORPHYRIN-BASED POLYSILSESQUIOXANE NANOMATERIALS FOR PHOTODYNAMIC THERAPY
- Author
- Vega, Daniel
- Date Created
- 2015
- Subjects--Topical
- Materials science, Chemistry, Nanotechnology
- Description
- Photodynamic Therapy (PDT) is a minimally invasive clinically approved cancertreatment that was first applied in the early 20th century. PDT is an attractive alternative when compared to chemotherapy and radiation therapy due to the lack of harmfu...
- Title
- DISTANCE-DEPENDENCE OF PLASMON-MULTIEXCITON COUPLING BETWEEN CDSE QUANTUM DOTS AND GOLD NANOSTRUCTURES
- Author
- Castaneda, Jose
- Date Created
- 2015
- Subjects--Topical
- Chemistry, Chemistry, Physical and theoretical
- Description
- Quantum confinement that semiconductors experience at the nanoscale facilitate the creation of multiexcitons. However, this same confinement also increases the efficiency of Auger recombination which result in low quantum yields from these states....
- Title
- Design, Synthesis, Characterization and Simulation of Polyhedral Oligomeric Silsesquioxane Porphyrin Molecules to Fabricate Self-Assembled Nanoparticles and Their Use for Photodynamic Therapy
- Author
- Loman-Cortes, Paula
- Date Created
- 2021
- Subjects--Topical
- Nanoscience
- Description
- PAULA LOMAN-CORTES. Design, Synthesis, Characterization and Simulation of Polyhedral Oligomeric Silsesquioxane Porphyrin Molecules to Fabricate Self-Assembled Nanoparticles and Their Use for Photodynamic Therapy. (Under the direction of DR JUAN L ...
- Title
- Determining the Rate of Ligand-Induced Charge-Transfer Effects on Quantum Dots
- Author
- Bowman, Cale
- Date Created
- 2015
- Subjects--Topical
- Chemistry
- Description
- In this report, charge carrier dynamics and rate of electron transfer is investigated between two bis(thioether)silane (R2BtsMe) ligands and 2.65 nm CdSe core quantum dots (QDs). Isothermal titration calorimetry (ITC) data is used to determine bin...
- Title
- Development of a Surface Enhanced Raman Spectroscopy-based Assay to Detect Malaria Biomarkers in Blood
- Author
- Hamm, Logan
- Date Created
- 2020
- Subjects--Topical
- Chemistry
- Description
- Malaria is an infectious disease that affects many lives around the world and eradication efforts are focused on controlling the disease transmission; which requires early diagnosis of the infection before the onset of symptoms, i.e. at the asympt...
- Title
- Development of nanoparticle-based approaches for the treatment and imaging of pancreatic cancer
- Author
- Tarannum, Mubin
- Date Created
- 2020
- Subjects--Topical
- Nanoscience, Chemistry
- Description
- Pancreatic ductal adenocarcinoma (PDAC) is a type of exocrine pancreatic cancer which accounts for over 90% of cases. PDAC is the fourth-leading cause of cancer-related mortality in the United States with a 5-year survival rate of 9% with little t...
- Title
- ELUCIDATING THE MOLECULAR BASIS OF INHIBITION OF ENZYMES ESSENTIAL FOR BATERIALVIRULENCE: THE ACTIVITY OF THREE GLYCOSYLTRANSFERASES AND A POTENTIAL DRUG TARGET, UNDECAPRENYL PYROPHOSPHATE SYNTHASE
- Author
- Okwei, Elleansar
- Date Created
- 2016
- Subjects--Topical
- Chemistry, Biology, Biochemistry
- Description
- The fight against bacterial infection is one of the most important branches of modern medicine. Due to the emergence of strains of antibiotic-resistant bacteria, researchers have been presented with complex challenges in an effort to combat these ...
- Title
- Early Detection of Malaria Parasitic RNA Through an Amplification-Free Surface-Enhanced Raman Spectroscopy Biosensor
- Author
- Blackwell, Ashley
- Date Created
- 2022
- Subjects--Topical
- Chemistry
- Description
- Malaria retains its position as one of the most highly transferable diseases throughout the world today, with current efforts focused on controlling its spread. A sensitive, asymptomatic-stage detection method is needed to diagnose malaria before ...
- Title
- Exceptional New Reagents for Bioconjugation
- Author
- Garmon, Corey
- Date Created
- 2016
- Subjects--Topical
- Chemistry, Biochemistry
- Description
- At about the turn of this century the term "click" chemistry came into the common vernacular amongst chemists. "Click" is used to describe reactions that are "spring-loaded" and proceed well in a predictable manner, with no offensive byproduct and...
- Title
- FUNCTIONAL NUCLEIC ACID NANOPARTICLES AND THEIR DELIVERY
- Author
- Ke, Weina
- Date Created
- 2020
- Subjects--Topical
- Biochemistry, Cytology
- Description
- Nucleic acid biopolymers are essential to all living organisms. The chemical makeup of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) consist of sequences of only four monomers. However, they transmit and express genetic information for va...
- Title
- FUNCTIONALIZATION AND CHARACTERIZATION OF NOVEL COORDINATION COMPLEXES FOR USE IN SUPERCAPACITORS
- Author
- Zuczek, Justin
- Date Created
- 2018
- Subjects--Topical
- Materials science, Power resources
- Description
- As society begins to move away from fossil fuel consumption and the harmful effects they entail, renewable energy sources have been studied extensively over the past decades. One obstacle with renewable energy is the ability to cheaply store it du...