Search results
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Title
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ALGORITHMS FOR STRUCTURE BASED-PREDICTION OF TRANSCRIPTION FACTOR BINDING SITES
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Author
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Farrel, Alvin
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Date Created
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2016
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Subjects--Topical
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Computer science, Biology, Bioinformatics
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Description
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Transcription factors (TFs) regulate gene expression through binding to specific target DNA sites. Accurate annotation of transcription factor binding sites (TFBSs) at genome scale represents an essential step toward our understanding of gene regu...
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Title
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An Integrated Phylogeographic Analysis of the Bantu Migration
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Author
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Ford, Colby
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Date Created
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2018
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Subjects--Topical
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Computer science, Mathematics, Genetics
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Description
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"Bantu" is a term used to describe lineages of people in around 600 different ethnic groups on the African continent ranging from modern-day Cameroon to South Africa. The migration of the Bantu people, which occurred around 3,000 years ago, was in...
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Title
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Arboviruses: The hidden path of an imminent threat
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Author
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de Bernardi Schneider, Adriano
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Date Created
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2018
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Subjects--Topical
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Virology, Bioinformatics, Epidemiology
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Description
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Arboviruses are a grade of viruses carried by arthropods, which have been in the headlines due to recent epidemics. Members of this grade are the families Flaviviridae which includes Zika (ZIKV), Dengue (DENV), Yellow Fever (YFV), among other viru...
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Title
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COMPARATIVE ANALYSIS OF REPEAT LANDSCAPES IN AVENA (OAT)
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Author
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Burkes, Shelvasha
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Date Created
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2020
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Subjects--Topical
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Biology, Bioinformatics, Botany
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Description
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Avena sativa, or common oat, is a staple crop and member of the Poaceae or Grass family. Following behind wheat, maize and rice, oats account for 10.5 million hectares of the world’s produced crops as of 2017. Phytocompounds such as β-glucan, aven...
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Title
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DE NOVO PREDICTION OF CIS-REGULATORY MODULES IN EUKARYOTIC ORGANISMS
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Author
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Niu, Meng
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Date Created
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2014
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Subjects--Topical
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Bioinformatics
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Description
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Gene regulation networks (GRNs) are the bases for virtually all biological processes. To gain a global understanding of GRNs encoded in a genome, we first need to identify in all the cis-regulatory elements (CREs) recognized by transcription facto...
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Title
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ELUCIDATING FUNCTIONAL MECHANISMS IN PROTEINS USING THE DISTANCE CONSTRAINT MODEL
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Author
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Singer, Christopher
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Date Created
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2019
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Subjects--Topical
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Bioinformatics, Biophysics, Physics
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Description
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Protein thermodynamics has been shown to be insightful and illuminating to the functional mechanisms behind biological function. By characterizing proteins and protein families according to their enthalpy and entropy we can make inferences to the ...
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Title
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Echinoderm Transcriptomics
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Author
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Linchangco, Gregorio
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Date Created
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2018
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Subjects--Topical
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Bioinformatics
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Description
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Tissue regeneration and biomineralization are expressed to a diverse extent across metazoans and their life stages. The potential for repair and regrowth in adult stages varies widely within phyla, class and species. For instance, few adult human ...
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Title
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Elucidation of miRNAs in Avena sativa
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Author
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Sheridan, Jaime
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Date Created
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2014
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Subjects--Topical
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Bioinformatics, Agriculture
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Description
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Micro RNAs (miRNAs) are a class of small non-coding RNAs with post-transcriptional gene regulation responsibilities. In plants, miRNAs regulate development of leaves, roots, shoots, and flowers through targeting families of transcription factors a...
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Title
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Functional Analysis of Structural Variation in the 2D and 3D Human Genome
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Author
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Nodzak, Conor
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Date Created
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2019
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Subjects--Topical
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Bioinformatics, Genetics
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Description
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The human genome consists of over 3 billion nucleotides that have an average distance of 3.4 Angstroms between each base, which equates to over two meters of DNA contained within the 125 $\mu m^3$ volume diploid cell nuclei. The dense compaction o...
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Title
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GENETIC MECHANISMS OF OZONE TOLERANCE IN SOYBEAN AND METHODS OF EVOLUTIONARY DISTANCE
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Author
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Whaley, Adam
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Date Created
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2015
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Subjects--Topical
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Bioinformatics, Genetics
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Description
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At ground level, ozone is a pollutant that poses serious risk to both human health and crop yields. In addition to being a vital economic crop in the US and abroad, conventional soybean lines are susceptible to damage caused by ozone exposure. In ...
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Title
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INVESTIGATING THE GENETIC BASIS OF GENE EXPRESSION USING EQTL TECHNIQUES
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Author
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Quitadamo, Andrew
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Date Created
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2018
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Subjects--Topical
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Bioinformatics
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Description
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With advances in genome sequencing technology, datasets with large sample sizes can be generated relatively quickly and cheaply, especially compared to the past decade or so. We can utilize this data to analyze the associations between genetic var...
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Title
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Integrative Network Approaches to Understanding MicroRNA and Gene Expressions in Cancer
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Author
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Hall, Benika
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Date Created
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2017
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Subjects--Topical
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Computer science, Bioinformatics, Medical sciences
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Description
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Cancer is among the leading cause of deaths in men and women today. Regulation of gene expression by microRNAs (miRNA) has been linked to cancer progression in recent years. Therefore there has been a growing interest understanding how miRNAs medi...
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Title
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Investigating the Molecular Mechanisms of Essential Oils on Human Health
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Author
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Uppal, Aneeta
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Date Created
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2020
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Subjects--Topical
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Molecular biology, Bioinformatics, Botany
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Description
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The essential oil (EO) industry continues to grow as consumers search for more alternative and complementary therapies. When possible, EO users often turn to EOs for basic medical ailments instead of traditional medications/pharmaceuticals. With t...
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Title
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Microbial Mutations - Accumulation in Microfluidics and Collateral Sensitivity
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Author
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Turner, Nathan
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Date Created
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2023
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Subjects--Topical
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Bioinformatics
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Description
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Mutations are a primary source of genetic variation and a major driving force in evolution by influencing survivability (fitness), genetic disease, and the development of complex traits such as antibiotic resistance. However, studying the mutation...