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Influence of cationic meso-substituted porphyrins on the antimicrobial photodynamic efficacy and cell membrane interaction in Escherichia coli
Title
Influence of cationic meso-substituted porphyrins on the antimicrobial photodynamic efficacy and cell membrane interaction in Escherichia coli
Author
Vivero-Escoto, Juan, Hurst, Alexandra N., Scarbrough, Beth, Troutman, Jerry M.
Subjects--Topical
Escherichia coli, Gram-negative bacteria
Description
Photodynamic inactivation (PDI) is a non-antibiotic option for the treatment of infectious diseases. Although Gram-positive bacteria have been shown to be highly susceptible to PDI, the inactivation of Gram-negative bacteria has been more challeng...
Mesoporous silica nanoparticles loaded with cisplatin and phthalocyanine for combination chemotherapy and photodynamic therapy in vitro
Title
Mesoporous silica nanoparticles loaded with cisplatin and phthalocyanine for combination chemotherapy and photodynamic therapy in vitro
Author
Vivero-Escoto, Juan, Elnagheeb, Maram
Subjects--Topical
Chemotherapy, Cancer
Description
Mesoporous silica nanoparticles (MSNs) have been synthesized and loaded with both aluminum chloride phthalocyanine (AlClPc) and cisplatin as combinatorial therapeutics for treating cancer. The structural and photophysical properties of the MSN mat...