Search results
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Title
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The immunorecognition, subcellular compartmentalization, and physicochemical properties of nucleic acid nanoparticles can be controlled by composition modification
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Author
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Johnson, M. Brittany, Halman, Justin, Marriott, Ian, Afonin, Kirill A., Miller, Daniel K., Cooper, Joseph S., Khisamutdinov, Emil F.
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Subjects--Topical
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Immunology, Nucleic acids, Nanoparticles
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Description
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Nucleic acid nanoparticles (NANPs) have become powerful new platforms as therapeutic and diagnostic tools due to the innate biological ability of nucleic acids to identify target molecules or silence genes involved in disease pathways. However, th...
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Title
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Therapeutic immunomodulation by rationally designed nucleic acids and nucleic acid nanoparticles (NANPs)
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Author
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Panigaj, Martin, Skelly, Elizabeth, Beasock, Damian, Marriott, Ian
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Date Created
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2023
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Subjects--Topical
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Immunology, Immune response--Regulation
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Description
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The immune system has evolved to defend organisms against exogenous threats such as viruses, bacteria, fungi, and parasites by distinguishing between self and non-self. In addition, it guards us against other diseases, such as cancer, by detecting...
