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Hepatic Stellate Cell Transdifferentiation: Pro-fibrogenic Effectors
Title
Hepatic Stellate Cell Transdifferentiation: Pro-fibrogenic Effectors
Author
Lakner, Ashley
Date Created
2011
Subjects--Topical
Molecular biology, Biology
Description
Hepatic fibrosis is a significant cause of morbidity and mortality worldwide and can be described as exacerbated wound-healing marked by excessive deposition of extracellular matrix components, predominantly type I collagen. Chronic injury stimula...
Hydrogen Sulfide Modulates Hepatic Oxygen Availability and Microcirculation during Sepsis
Title
Hydrogen Sulfide Modulates Hepatic Oxygen Availability and Microcirculation during Sepsis
Author
Norris, Eric
Date Created
2012
Subjects--Topical
Biology, Physiology
Description
A mismatch between O2 supply and demand leads to the development of tissue hypoxia which contributes to hepatic dysfunction and injury during sepsis. Previously, we reported that hepatic microcirculatory failure is a major contributor to hypoxia a...