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ENGINEERING OXYGEN TRANSPORT FOR IMPROVING CELL PERFORMANCE IN HEPATIC DEVICES
Title
ENGINEERING OXYGEN TRANSPORT FOR IMPROVING CELL PERFORMANCE IN HEPATIC DEVICES
Author
Shi, Gengbei
Date Created
2012
Subjects--Topical
Mechanical engineering, Biomedical engineering
Description
The bioartificial liver (BAL) advancing medical technology aims to provide temporary liver substitution for patients in dire need of liver transplants and also for drug development. Yet despite nearly fifty years of development, the approval for t...
Hydrogen Sulfide Modulates Hepatic Oxygen Availability and Microcirculation during Sepsis
Title
Hydrogen Sulfide Modulates Hepatic Oxygen Availability and Microcirculation during Sepsis
Author
Norris, Eric
Date Created
2012
Subjects--Topical
Biology, Physiology
Description
A mismatch between O2 supply and demand leads to the development of tissue hypoxia which contributes to hepatic dysfunction and injury during sepsis. Previously, we reported that hepatic microcirculatory failure is a major contributor to hypoxia a...