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Title: Hepatic Stellate Cell Transdifferentiation: Pro-fibrogenic Effectors
Author: Lakner, Ashley
Date Created: 2011
Subjects--Topical: Molecular biology, Biology
Description: Hepatic fibrosis is a significant cause of morbidity and mortality worldwide and can be described as exacerbated wound-healing marked by excessive deposition of extracellular matrix components, predominantly type I collagen. Chronic injury stimula...

Title: Hydrogen Sulfide Modulates Hepatic Oxygen Availability and Microcirculation during Sepsis
Author: Norris, Eric
Date Created: 2012
Subjects--Topical: Biology, Physiology
Description: A mismatch between O_{2_{supply and demand leads to the development of tissue hypoxia which contributes to hepatic dysfunction and injury during sepsis. Previously, we reported that hepatic microcirculatory failure is a major contributor to hypoxia a...}}

Title: Interaction between hydrogen sulfide and endothelin-1 in hepatic perfusion and mitochondrial dynamics in endotoxemia
Author: Pennington, Samantha
Date Created: 2018
Subjects--Topical: Physiology, Cytology
Description: A mismatch between oxygen supply and metabolic tissue demand leads to the development of hypoxia, which contributes to hepatic dysfunction and liver injury during sepsis. Recent evidence shows that hepatic H2S levels are increased during sepsis an...

Title: Role of Nonmuscle Myosin II in Hepatic Stellate Cell Activation
Author: Moore, Cathy
Date Created: 2009
Subjects--Topical: Molecular biology
Description: The hepatic stellate cell (HSC) plays a pivotal role in the development of hepatic fibrosis. Regulation of liver microcirculation is a complex system where blood flow is under systemic and sinusoidal control. Upon a fibrogenic stimulus, quiescent ...