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Role of Nonmuscle Myosin II in Hepatic Stellate Cell Activation
Title
Role of Nonmuscle Myosin II in Hepatic Stellate Cell Activation
Author
Moore, Cathy
Date Created
2009
Subjects--Topical
Molecular biology
Description
The hepatic stellate cell (HSC) plays a pivotal role in the development of hepatic fibrosis. Regulation of liver microcirculation is a complex system where blood flow is under systemic and sinusoidal control. Upon a fibrogenic stimulus, quiescent ...
EFFECTS OF S-ADENOSYL-L-METHIONINE ON COLLAGEN EXPRESSION IN ACTIVATED HEPATIC STELLATE CELLS
Title
EFFECTS OF S-ADENOSYL-L-METHIONINE ON COLLAGEN EXPRESSION IN ACTIVATED HEPATIC STELLATE CELLS
Author
Thompson, Kyle
Date Created
2009
Subjects--Topical
Biology, Cytology
Description
Liver fibrosis is defined as the excessive accumulation of extracellular matrix (ECM) components, which can disrupt the normal liver microcirculation and lead to injury. Unresolved, hepatic fibrosis can progress to cirrhosis, an end-state liver di...