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THE DEVELOPMENT OF NOVEL THERAPEUTICS IN PANCREATIC AND BREAST CANCERS: POTENTIAL ROLE OF MUC1
Title
THE DEVELOPMENT OF NOVEL THERAPEUTICS IN PANCREATIC AND BREAST CANCERS: POTENTIAL ROLE OF MUC1
Author
Besmer, Dahlia
Date Created
2013
Subjects--Topical
Biology
Description
Pancreatic ductal adenocarcinoma (PDA) is the 4th leading cause of cancer-related deaths in the US, and breast cancer (BC) contributes to ~40,000 deaths annually. The development of novel therapeutic agents for improving patient outcome is of para...
How Do the Homeless Newly Diagnosed With Cancer Receive Safe and Cost-Effective HealthCare Year One Following Diagnosis?
Title
How Do the Homeless Newly Diagnosed With Cancer Receive Safe and Cost-Effective HealthCare Year One Following Diagnosis?
Author
Edinger, Amy
Date Created
2021
Subjects--Topical
Nursing
Description
ABSTRACTAMY B. EDINGER. How Do the Homeless Newly Diagnosed with Cancer Receive Safe and Cost-Effective Healthcare During Year One Following Diagnosis? (Under the direction of DR. STEPHANIE WOODS) Cancer is one of the most common causes of mortali...
Folate Receptor-Specific, Redox-Responsive Mesoporous Silica Nanoparticles for the Simultaneous Delivery of Cisplatin and Gemcitabine to Treat Cancer
Title
Folate Receptor-Specific, Redox-Responsive Mesoporous Silica Nanoparticles for the Simultaneous Delivery of Cisplatin and Gemcitabine to Treat Cancer
Author
Fink, Eric
Date Created
2016
Subjects--Topical
Materials science, Chemistry, Biochemistry
Description
Nanoparticles are an innovative platform for cancer treatment that reduces systemic toxicity and allows for active targeting of tumor sites to enhance the therapeutic efficacy. Mesoporous silica nanoparticles (MSNs) have emerged as an attractive d...
MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
Title
MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
Author
Grover, Priyanka
Date Created
2019
Subjects--Topical
Biology
Description
In 2019, Pancreatic Cancer (PC) is the 3rd leading cause of cancer-related deaths in the USA with 94% dying within 5 years of diagnosis. 90% of PC is Pancreatic Ductal Adenocarcinoma (PDA), of which >80% overexpress a hypo-glycosylated form the me...
Understanding and overcoming limitations of vesicular stomatitis virus as an oncolytic agent against pancreatic ductal adenocarcinoma
Title
Understanding and overcoming limitations of vesicular stomatitis virus as an oncolytic agent against pancreatic ductal adenocarcinoma
Author
Hastie, Eric
Date Created
2014
Subjects--Topical
Virology, Biology
Description
Vesicular stomatitis virus (VSV) is a prototypic nonsegmented negative-strand RNA virus. Lack of preexisting immunity against VSV, inherent oncotropism, and genetic malleability make VSV a widely used platform for vaccine, oncolytic, and gene ther...
ROLE OF AQUAPORINS DURING HEPATOCELLULAR CARCINOMA INITIATION AND PROGRESSION
Title
ROLE OF AQUAPORINS DURING HEPATOCELLULAR CARCINOMA INITIATION AND PROGRESSION
Author
Mattocks, Matthew
Date Created
2010
Subjects--Topical
Molecular biology, Cytology, Oncology
Description
Aquaporins (AQPs) are ubiquitously expressed proteinaceous water channels involved in numerous physiological processes including bile production and apoptosis. Aquaporins 8 and 9 are expressed in hepatocytes, and are down regulated in a rat model ...
Breaking Down Barriers to Goals of Care Discussions With Terminally Ill Cancer Patients
Title
Breaking Down Barriers to Goals of Care Discussions With Terminally Ill Cancer Patients
Author
Poillucci, Victoria
Date Created
2021
Subjects--Topical
Communication, Medical sciences, Oncology
Description
Opportunities to discuss options for care when faced with a life limiting disease is the right of all patients. Yet, healthcare provider feelings of awkwardness, fear of diminishing hope, and fear of failing to cure can result in missed opportunit...
PATIENT AND PROVIDER LEVEL PREDICTORS OF BREAST SURGEONS’ PRACTICE STYLES AND MODALITY APPROACHES FOR MASTECTOMY PROCEDURES
Title
PATIENT AND PROVIDER LEVEL PREDICTORS OF BREAST SURGEONS’ PRACTICE STYLES AND MODALITY APPROACHES FOR MASTECTOMY PROCEDURES
Author
Shahbazi, Sara
Date Created
2017
Subjects--Topical
Medical sciences
Description
ABSTRACTSARA SHAHBAZI. Patient and Provider Level Predictors of Breast Surgeons’ Practice Styles and Modality Approaches for Mastectomy Procedures(Under the direction of DR. LARISSA R. BRUNNER HUBER)Background: Breast cancer surgery, including mas...
Data Mining the Serous Ovarian Tumor Transcriptome
Title
Data Mining the Serous Ovarian Tumor Transcriptome
Author
Tickle, Timothy
Date Created
2011
Subjects--Topical
Bioinformatics, Genetics
Description
Ovarian cancer is the most lethal gynecologic cancer in the United States. If caught in early stages, patient survival rate is 94%, late stage survival rates drop to 28%. It is because most cases are caught in late stages that high mortality is se...
NEOPLASTIC DISEASES IN PRE-HISPANIC ANDEANS: A COMPARATIVE ANALYSIS ON THE EFFECTS OF ALTITUDE BETWEEN THE HIGHLANDS AND COASTAL REGIONS
Title
NEOPLASTIC DISEASES IN PRE-HISPANIC ANDEANS: A COMPARATIVE ANALYSIS ON THE EFFECTS OF ALTITUDE BETWEEN THE HIGHLANDS AND COASTAL REGIONS
Author
Westbrook, Carita
Date Created
2019
Subjects--Topical
Archaeology
Description
This thesis is a comparative review of skeletal elements from coastal and highland regions of Peru to determine if altitude effects the incidence of skeletal cancer formations. Pathological analysis was completed on 372 skeletal elements: 299 elem...