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Elucidating Dynamic Mechanisms for Extended Spectrum Antibiotic Resistance in Class A Beta-Lactamase through Machine Learning on Molecular Dynamics Simulations
Title
Elucidating Dynamic Mechanisms for Extended Spectrum Antibiotic Resistance in Class A Beta-Lactamase through Machine Learning on Molecular Dynamics Simulations
Author
Avery, Christopher
Date Created
2019
Subjects--Topical
Biophysics, Physics
Description
Beta-lactamase is a protein which is produced in bacteria and is a primary cause of antibiotic resistance to Beta Lactam antibiotics. Beta Lactams are among the most common types of antibiotics (including penicillin) and thus understanding the res...
Long-term study of changes in microbiota in a Cystic Fibrosis patient
Title
Long-term study of changes in microbiota in a Cystic Fibrosis patient
Author
Stokell, Joshua
Date Created
2013
Subjects--Topical
Biology, Microbiology
Description
Application of culture-independent techniques have revealed the presence of more types of bacteria than were previously thought, which led to the current description of Cystic Fibrosis (CF) being a polymicrobial disease. We know this polymicrobial...
PHARMACEUTICALS IN THE ENVIRONMENT: PREVIOUSLY UNRECOGNIZED SOURCES IN WATER RESOURCES
Title
PHARMACEUTICALS IN THE ENVIRONMENT: PREVIOUSLY UNRECOGNIZED SOURCES IN WATER RESOURCES
Author
NETH, NICOLE
Date Created
2018
Subjects--Topical
Civil engineering, Environmental engineering, Water resources development--Management
Description
It is known that wastewater treatment plants are one of the major routes through which pharmaceuticals enter the environment. The following work investigated the effect of previously unrecognized sources of pharmaceuticals that enter water resourc...
THE SYNTHESIS OF PHOTOSENSITIZERS FOR THE PHOTODYNAMIC INACTIVATION OF ESCHERICHIA COLI
Title
THE SYNTHESIS OF PHOTOSENSITIZERS FOR THE PHOTODYNAMIC INACTIVATION OF ESCHERICHIA COLI
Author
Hurst, Alexandra
Date Created
2017
Subjects--Topical
Chemistry
Description
The development of antibiotic resistance is a natural phenomenon that occurs when bacteria cells exchange resistant traits amongst each other or when mutations occur during replication. This causes bacteria to be able to withstand attack by antibi...
The Microbiota Multiverse: From Gut to Brain and Beyond
Title
The Microbiota Multiverse: From Gut to Brain and Beyond
Author
Brown, Matthew
Date Created
2019
Subjects--Topical
Microbiology, Bioinformatics
Description
This work explores the microbiomes of diverse biological contexts with various stakeholders and collaborators. It consists of six objectives: the first two relate to interaction between the gut microbiome and host health, the second two investigat...
The in-vivo Evolution of Burkholderia multivorans in a Cystic Fibrosis patient
Title
The in-vivo Evolution of Burkholderia multivorans in a Cystic Fibrosis patient
Author
Harrison, Sarah
Date Created
2021
Subjects--Topical
Biology, Microbiology, Bioinformatics
Description
ABSTRACT Burkholderia multivorans is an opportunistic pathogen that poses a health risk to patients with cystic fibrosis (CF). The use of broad-range antibiotics to combat chronic bacterial lung infections has led to the evolution of antibiotic-re...
The influence of wastewater treatment on community dynamics among antibiotic-resistant bacteria during treatment, stream release, and biosolids land application.
Title
The influence of wastewater treatment on community dynamics among antibiotic-resistant bacteria during treatment, stream release, and biosolids land application.
Author
Sorgen, Alicia
Date Created
2020
Subjects--Topical
Microbiology, Bioinformatics, Ecology
Description
Wastewater treatment plants (WWTP) are a key link between anthropogenic activity and the environment, facilitating the development and horizontal transfer of antibiotic resistance among populations of commensal environmental microorganisms and cli...