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Cholera Toxin Subunit B-Mediated Intracellular Trafficking of Mesoporous Silica Nanoparticles Toward the Endoplasmic Reticulum
Title
Cholera Toxin Subunit B-Mediated Intracellular Trafficking of Mesoporous Silica Nanoparticles Toward the Endoplasmic Reticulum
Author
Walker, William
Date Created
2015
Subjects--Topical
Materials science, Nanoscience, Biomedical engineering
Description
In recent decades, pharmaceutical research has led to the development of numerous treatments for human disease. Nanoscale delivery systems have the potential to maximize therapeutic outcomes by enabling target specific delivery of these therapeuti...
DOPAMINE DETECTION VIA SURFACE ENHANCED RAMAN SCATTERING FOR PARKINSON’S DISEASE
Title
DOPAMINE DETECTION VIA SURFACE ENHANCED RAMAN SCATTERING FOR PARKINSON’S DISEASE
Author
Cutler, Eric
Date Created
2019
Subjects--Topical
Mechanical engineering, Biomedical engineering
Description
Motion is controlled via the excitatory or inhibitory responses of the motor pathway by receptors in Substantia Nigra of the brain, modulated by a main neurotransmitter dopamine (DA). Parkinson’s Disease (PD) is the neurological disorder effecting...
Design of a Microstrip Antenna and PCB for use in an Electrocorticography Biomedical Implant
Title
Design of a Microstrip Antenna and PCB for use in an Electrocorticography Biomedical Implant
Author
West, Jakob
Date Created
2019
Subjects--Topical
Electrical engineering, Biomedical engineering, Electromagnetism
Description
An implantable system, that is part of a wireless body area network, is under development for a study monitoring of neural activity in rats with epilepsy. The study will continue over a nine month period to collect data for epilepsy research. This...
Development of injectable bioceramic drug delivery system for solid tumor treatment
Title
Development of injectable bioceramic drug delivery system for solid tumor treatment
Author
Haig, James
Date Created
2017
Subjects--Topical
Materials science, Engineering, Biomedical engineering
Description
According to the national cancer institute "In 2016, an estimated 1,685,210 new cases of cancer will be diagnosed in the United States and 595,690 people will die from the disease" and "The number of people living beyond a cancer diagnosis reached...
EFFECT OF BIOCERAMIC FUNCTIONAL GROUPS ON DRUG BINDING AND RELEASE KINETICS
Title
EFFECT OF BIOCERAMIC FUNCTIONAL GROUPS ON DRUG BINDING AND RELEASE KINETICS
Author
Trujillo, Christopher
Date Created
2015
Subjects--Topical
Materials science, Engineering, Biomedical engineering
Description
Bioceramics have been studied extensively as drug delivery systems (DDS). Those studies have aimed to tailor the drug binding and release kinetics to successfully treat infections and other diseases. This research suggests that the drug binding an...
PREPARATION AND VISUALIZATION OF INDIVIDUAL ACTIN FILAMENTS USING ATOMIC FORCE MICROSCOPY FOR THE STUDY OF ACTIN/DNA HYDROGEL COMPLEXES
Title
PREPARATION AND VISUALIZATION OF INDIVIDUAL ACTIN FILAMENTS USING ATOMIC FORCE MICROSCOPY FOR THE STUDY OF ACTIN/DNA HYDROGEL COMPLEXES
Author
Kennedy, Joshua
Date Created
2019
Subjects--Topical
Physics, Biophysics, Biomedical engineering
Description
A protocol of sample preparation for the visualization of single actin filaments at the nanoscale using atomic force microscopy for use in studies of engineered actin/DNA conjugated hydrogel complexes was developed. Hydrogels are cross-linked netw...
SINGLE-STEP, REDUCED SHEAR, MICROFLUIDIC EXTRUSION OF BLOOD BRAIN BARRIER
Title
SINGLE-STEP, REDUCED SHEAR, MICROFLUIDIC EXTRUSION OF BLOOD BRAIN BARRIER
Author
Wetzel, Isaac
Date Created
2019
Subjects--Topical
Biomedical engineering
Description
Three-dimensional (3D) bioprinting of living structures with cell-laden biomaterials has been achieved in vitro, however, central nervous system tissues have been limited by the low viability printing of cerebral vessels, using conventional printi...