Search results
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Title
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Exceptional New Reagents for Bioconjugation
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Author
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Garmon, Corey
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Date Created
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2016
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Subjects--Topical
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Chemistry, Biochemistry
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Description
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At about the turn of this century the term "click" chemistry came into the common vernacular amongst chemists. "Click" is used to describe reactions that are "spring-loaded" and proceed well in a predictable manner, with no offensive byproduct and...
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Title
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Exploring the Immune System using Hybrid Cube Nanoparticles
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Author
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McMillan, Jessica
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Date Created
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2021
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Subjects--Topical
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Biochemistry, Nanotechnology, Biology
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Description
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Nano-sized cubes made from nucleic acid material (NANPs) are ideal scaffolds for therapeutic nucleic acids (TNAs). Both utilize sequence specificity through base-pairing, providing controlled strand interaction, stability, and targeted targeting d...
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Title
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Halogenated Tags for the Investigation of Enzyme Specificity
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Author
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Houde, Hailey
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Date Created
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2023
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Subjects--Topical
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Biochemistry, Chemistry
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Description
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The bacterial enzyme undecaprenyl pyrophosphate synthase (UppS) is present in most prokaryotes and is needed for bacterial survival. UppS produces the essential lipid carrier, bactoprenyl monophosphate (BP). BP is critical for the structural integ...
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Title
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INCORPORATION OF FLUORESCENT ANALOGUES IN ISOPRENOID PATHWAYS IN ESCHERICHIA COLI
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Author
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George, Chelsea
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Date Created
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2018
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Subjects--Topical
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Biochemistry
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Description
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Bacterial glycans and glycoconjugates have wide diversity compared to their eukaryotic counterparts. While methods have been developed to monitor and track glycans in eukaryotic systems with some success, there are limited methods with which to do...
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Title
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NUCLEIC ACID-DRIVEN QUANTUM DOT-BASED LATTICE FORMATIONS FOR BIOMEDICAL APPLICATIONS
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Author
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Roark, Brandon
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Date Created
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2017
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Subjects--Topical
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Nanoscience, Nanotechnology, Biochemistry
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Description
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We present a versatile biosensing strategy that uses nucleic acids programmed to undergo an isothermal toehold mediated strand displacement in the presence of analyte. This rearrangement results in a double biotinylated duplex formation that induc...
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Title
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ORGANIZATION OF BIOMOLECULES IN A 3-DIMENSIONAL SPACE
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Author
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Sajja, Sameer
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Date Created
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2019
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Subjects--Topical
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Nanotechnology, Biochemistry
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Description
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The human body operates using various stimuli-responsive mechanisms, dictating biological activity via reaction to external cues. Hydrogels are networked hydrophilic polymeric materials that offer the potential to recreate aqueous environments wit...
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Title
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ORGANIZATION OF BIOMOLECULES IN A 3-DIMENSIONAL SPACE
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Author
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Sajja, Sameer
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Date Created
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2019
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Subjects--Topical
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Biochemistry
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Description
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The human body operates using various stimuli-responsive mechanisms, dictating biological activity via reaction to external cues. Hydrogels are networked hydrophilic polymeric materials that offer the potential to recreate aqueous environments wit...