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Assessing the Biological Activities of DNA-Templated Silver Nanoclusters and Furthering the Characterization of Nucleic Acid Nanoparticles
Title
Assessing the Biological Activities of DNA-Templated Silver Nanoclusters and Furthering the Characterization of Nucleic Acid Nanoparticles
Author
Rolband, Lewis
Date Created
2023
Subjects--Topical
Biochemistry
Description
DNA and RNA are structurally and functionally diverse biopolymers that haveshown promise in recent years as a powerful biomedical tool, in the form of nucleic acid nanotechnologies. The applications of these technologies include biosensing, diagno...
Design and Modulation of Novel Chemical Probes for RNA SHAPE Analysis: Water Soluble Isatoic Anhydrides and Nicotinic Acid Imidazolides
Title
Design and Modulation of Novel Chemical Probes for RNA SHAPE Analysis: Water Soluble Isatoic Anhydrides and Nicotinic Acid Imidazolides
Author
Fessler, Adam
Date Created
2021
Subjects--Topical
Chemistry, Biology
Description
The growing interest in RNA biology, along with an expansion in computational capabilities, throughput, and sensitivity has provided researchers new tools to probe RNA. RNA selective 2′-hydroxy acylation analyzed by primer extension (SHAPE) utiliz...
Dynamic and Conditionally Activated Nucleic Acid Nanoparticles
Title
Dynamic and Conditionally Activated Nucleic Acid Nanoparticles
Author
Chandler, Morgan
Date Created
2021
Subjects--Topical
Nanoscience
Description
Programmed interactions of nucleic acids—including DNA and RNA—orchestrate genetic expression and downstream cellular processes at every level. The structures of nucleic acids rely on their sequences, which include traditional Watson-Crick base pa...