Search results | J. Murrey Atkins Library

Title: A chromosome-level genome assembly of the highly heterozygous sea urchin Echinometra sp. EZ reveals adaptation in the regulatory regions of stress response genes
Author: Reitzel, Adam M., Ketchum, Remi, Smith, Edward, Davidson, Phillip L.
Date Created: 2022
Subjects--Topical: Sea urchins, Echinodermata
Description: Echinometra is the most widespread genus of sea urchin and has been the focus of a wide range of studies in ecology, speciation, and reproduction. However, available genetic data for this genus are generally limited to a few select loci. Here, we ...

Title: A comparison of transgenic and wild type soybean seeds : analysis of transcriptome profiles using RNA-Seq
Author: Loraine, Ann, Lambirth, Kevin C., Whaley, Adam M., Piller, Kenneth J.
Date Created: 2015
Subjects--Topical: Gene expression, Biotechnology
Description: Background: Soybean (Glycine max) has been bred for thousands of years to produce seeds rich in protein for human and animal consumption, making them an appealing bioreactor for producing valuable recombinant proteins at high levels. However, the ...

Title: A new obligate CXCL4-CXCL12 heterodimer for studying chemokine heterodimer activities and mechanisms
Author: Nesmelova, Irina, Ngyuen, Khanh T.P., Dreau, Didier, Volkman, Brian
Date Created: 2022
Subjects--Topical: Chemokines, Proteins
Description: Chemokines form a family of proteins with critical roles in many biological processes in health and disease conditions, including cardiovascular, autoimmune diseases, infections, and cancer. Many chemokines engage in heterophilic interactions to f...

Title: A subterminal growth zone at arm tip likely underlies life-long indeterminate growth in brittle stars
Author: Janies, Daniel, Machado, Denis Jacob, Reid, Robert, Kofsky, Janice
Date Created: 2022
Subjects--Topical: Genomics, Biology
Description: Background Echinoderms are a phylum of marine invertebrates with close phylogenetic relationships to chordates. Many members of the phylum Echinodermata are capable of extensive post-traumatic regeneration and life-long indeterminate growth. Diffe...

Title: APE2 promotes DNA damage response pathway from a single-strand break
Author: Yan, Shan, Lin, Yunfeng, Bai, Liping, Cupello, Steven
Date Created: 2018
Subjects--Topical: Cancer--Research, DNA
Description: As the most common type of DNA damage, DNA single-strand breaks (SSBs) are primarily repaired by the SSB repair mechanism. If not repaired properly or promptly, unrepaired SSBs lead to genome stability and have been implicated in cancer and neurod...

Title: Acquired chemoresistance can lead to increased resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus
Author: Grdzelishvili, Valery, Goad, Dakota, Bressy, Christian, Holbrook, Molly
Subjects--Topical: Vesicular stomatitis, Cancer, Viruses
Description: Vesicular stomatitis virus (VSV) is a promising oncolytic virus (OV) against different malignancies, including pancreatic ductal adenocarcinoma (PDAC). Our previous studies have demonstrated that VSV-based OVs are effective against the majority of...

Title: Cell cycle arrest in G2/M phase enhances replication of interferon-sensitive cytoplasmic RNA viruses via inhibition of antiviral gene expression
Author: Grdzelishvili, Valery, Bressy, Christian, Droby, Gaith N., Maldonado, Bryant D., Steuerwald, Nury
Subjects--Topical: Cancer, Viruses
Description: Vesicular stomatitis virus (VSV) (a rhabdovirus) and its variant VSV-ΔM51 are widely used model systems to study mechanisms of virus-host interactions. Here, we investigated how the cell cycle affects replication of these viruses using an array of...

Title: Cellular bioreactivity of micro- and nano-plastic particles in oysters
Author: Gaspar, Tamara R., Chi, Richard J., Parrow, Matthew W., Ringwood, Amy H.
Subjects--Topical: Plastics, Nanoparticles
Description: The global usage of plastics has increased dramatically over the last several decades. Polystyrene (PS) is the fourth most common plastic material produced annually due to its many versatile applications. Consequently, there has been a coinciding ...

Title: Combining oncolytic virotherapy with p53 tumor suppressor gene therapy
Author: Grdzelishvili, Valery, Bressy, Christian, Hastie, Eric Lawrence
Subjects--Topical: Cancer, Gene therapy
Description: Oncolytic virus (OV) therapy utilizes replication-competent viruses to kill cancer cells, leaving non-malignant cells unharmed. With the first U.S. Food and Drug Administration-approved OV, dozens of clinical trials ongoing, and an abundance of tr...

Title: Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications
Author: Truman, Andrew, Zheng, Bo, Omkar, Siddhi, Takakuwa, Jade E.
Date Created: 2022
Subjects--Topical: Proteins, Molecular biology
Description: Hsp70 interactions are critical for cellular viability and the response to stress. Previous attempts to characterize Hsp70 interactions have been limited by their transient nature and the inability of current technologies to distinguish direct ver...

Title: Convergent shifts in host-associated microbial communities across environmentally elicited phenotypes
Author: Reitzel, Adam M., Carrier, Tyler J.
Date Created: 2018
Subjects--Topical: Evolution (Biology), Biology
Description: Morphological plasticity is a genotype-by-environment interaction that enables organisms to increase fitness across varying environments. Symbioses with diverse microbiota may aid in acclimating to this variation, but whether the associated bacter...

Title: Creating an online scientific art exhibit formatted for people with a visual impairment
Author: Sorrell, Melanie, Norton, Derek R., McAdams, Jeff, Winterling, Rachael, Dipple, Kathleen
Subjects--Topical: People with visual disabilities, Accessible Web sites for people with disabilities, Academic libraries
Description: An online exhibit accessible by people with a visual impairment was created to accompany a university library’s physical exhibit of microscopic images generated by researchers on campus as “scientific art.” This online exhibit consisted of a Web p...

Title: Current perspectives of telomerase structure and function in eukaryotes with emerging views on telomerase in human parasites
Author: Chakrabarti, Kausik, Dey, Abhishek
Date Created: 2018
Subjects--Topical: Molecular biology, Evolution (Biology)
Description: Replicative capacity of a cell is strongly correlated with telomere length regulation. Aberrant lengthening or reduction in the length of telomeres can lead to health anomalies, such as cancer or premature aging. Telomerase is a master regulator f...

Title: Cytosolic DNA sensors and CNS responses to viral pathogens
Author: Marriott, Ian, Jeffries, Austin
Subjects--Topical: DNA, Virus diseases
Description: Viral central nervous system (CNS) infections can lead to life threatening encephalitis and long-term neurological deficits in survivors. Resident CNS cell types, such as astrocytes and microglia, are known to produce key inflammatory and antivira...

Title: Cytosolic DNA sensors and glial responses to endogenous DNA
Author: Marriott, Ian, Suptela, Alexander J.
Date Created: 2023
Subjects--Topical: Genomics, DNA
Description: Genomic instability is a key driving force for the development and progression of many neurodegenerative diseases and central nervous system (CNS) cancers. The initiation of DNA damage responses is a critical step in maintaining genomic integrity ...

Title: DNA extraction method plays a significant role when defining bacterial community composition in the marine invertebrate Echinometra mathaei
Author: Reitzel, Adam M., Ketchum, Remi, Carrier, Tyler J.
Date Created: 2018
Subjects--Topical: Bacteria, Biology
Description: The microbial assemblages of marine organisms play fundamental biological roles in their eukaryotic hosts. Studies aimed at characterizing this diversity have increased over the last decade and with the availability of high-throughput sequencing, ...

Title: Daily cycle in oxygen consumption by the sea anemone Nematostella vectensis Stephenson
Author: Reitzel, Adam M., Maas, Amy E., Jones, Ian T.
Date Created: 2016
Subjects--Topical: Gene expression, Biology
Description: In bilaterian animals, the circadian clock is intimately involved in regulating energetic metabolism. Although cnidarians exhibit diel behavioral rhythms including cycles in locomotor activity, tentacle extension and spawning, daily cycles in cnid...

Title: Decoupling behavioral and transcriptional responses to color in an eyeless cnidarian
Author: Reitzel, Adam M., Leach, Whitney
Subjects--Topical: Gene expression, Circadian rhythms
Description: Background Animals have specific molecular, physiological, and behavioral responses to light that are influenced by wavelength and intensity. Predictable environmental changes – predominantly solar and lunar cycles – drive endogenous daily oscilla...

Title: Detection of high prevalence of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Assosa zone, Ethiopia : implication for malaria diagnosis
Author: Janies, Daniel, Blackburn, Kayla, Lopez, Karen, Lo, Eugenia
Date Created: 2021
Subjects--Topical: Communicable diseases, Malaria
Description: Background Rapid diagnostic tests (RDTs) targeting histidine rich protein 2(HRP2) are widely used for diagnosis of Plasmodium falciparum infections. Besides PfHRP2, the PfHRP3 antigen contributes to the detection of P. falciparum infections in PfH...

Title: Developmental and light-entrained expression of melatonin and its relationship to the circadian clock in the sea anemone Nematostella vectensis
Author: Reitzel, Adam M., Peres, Rafael, Passamaneck, Yale
Date Created: 2014
Subjects--Topical: Gene expression, Biology
Description: Background: The primary hormone of the vertebrate pineal gland, melatonin, has been identified broadly throughout the eukaryotes. While the role for melatonin in cyclic behavior via interactions with the circadian clock has only been reported in v...