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EXPERIMENTAL EVOLUTION OF ONCOLYTIC VESICULAR STOMATITIS VIRUSES IN CANCER CELLS
Title
EXPERIMENTAL EVOLUTION OF ONCOLYTIC VESICULAR STOMATITIS VIRUSES IN CANCER CELLS
Author
Seegers, Sara
Date Created
2019
Subjects--Topical
Molecular biology, Virology, Biology
Description
Vesicular stomatitis virus (VSV) based oncolytic viruses are promising agents against various cancers. We have shown that pancreatic ductal adenocarcinoma (PDAC) cell lines exhibit great diversity in susceptibility and permissibility to VSV. Here,...
INVESTIGATING THE ROLE OF NEWLY DESCRIBED CYTOSOLIC PATTERN RECOGNITION RECEPTORS IN PROTECTIVE HOST RESPONSES TO NEUROTROPIC VIRUSES
Title
INVESTIGATING THE ROLE OF NEWLY DESCRIBED CYTOSOLIC PATTERN RECOGNITION RECEPTORS IN PROTECTIVE HOST RESPONSES TO NEUROTROPIC VIRUSES
Author
Crill, Emma
Date Created
2014
Subjects--Topical
Immunology, Virology
Description
The importance of the effector functions performed by glial cells, the resident cells of the CNS possessing immune functions, in abrogating potentially fatal neurotropic viral infections have only recently begun to gain appreciation. These effecto...
Study of the Intracellular Protein Tau and its Relationship with Kunjin Virus and Neurodegenerative Diseases
Title
Study of the Intracellular Protein Tau and its Relationship with Kunjin Virus and Neurodegenerative Diseases
Author
Lotz, Sarah
Date Created
2022
Subjects--Topical
Neurosciences, Immunology, Virology
Description
Neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis, comprise a family of disorders characterized by progressive loss of nervous system function. Neuroinflammation is increasingly recogni...