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RNA Kissing Loop Library to expand RNA Fiber functionality and control cargo load for potential intracellular siRNA delivery.
Title
RNA Kissing Loop Library to expand RNA Fiber functionality and control cargo load for potential intracellular siRNA delivery.
Author
Shevchenko, Oleg
Date Created
2020
Subjects--Topical
Nanoscience, Nanotechnology, Biochemistry
Description
A kissing loop (KL) is an RNA motif that among others may have a 180° geometry when derived from a viral genome. The KL interactions of this geometry consist of nine base pairs, six of which are interacting in complementary binding while three are...
GROWTH OF InGaN MATERIAL AND DEVICE STRUCTURES IN A HIGH PRESSURE MOCVD REACTOR
Title
GROWTH OF InGaN MATERIAL AND DEVICE STRUCTURES IN A HIGH PRESSURE MOCVD REACTOR
Author
Conway, Matthew
Date Created
2019
Subjects--Topical
Materials science, Electrical engineering, Nanotechnology
Description
This is an initial investigation of the super-atmospheric (1.5 – 2.5 bar(a)) Metal-Organic Chemical Vapor Deposition (MOCVD) growth of InGaN materials and experimental, device-like structures. The work was accomplished in a custom MOCVD reactor, s...
DESIGN, SYNTHESIS AND CHARACTERIZATION OF MULTIFUNCTIONAL REDOX-RESPONSIVE PORPHYRIN-BASED POLYSILSESQUIOXANE NANOMATERIALS FOR PHOTODYNAMIC THERAPY
Title
DESIGN, SYNTHESIS AND CHARACTERIZATION OF MULTIFUNCTIONAL REDOX-RESPONSIVE PORPHYRIN-BASED POLYSILSESQUIOXANE NANOMATERIALS FOR PHOTODYNAMIC THERAPY
Author
Vega, Daniel
Date Created
2015
Subjects--Topical
Materials science, Chemistry, Nanotechnology
Description
Photodynamic Therapy (PDT) is a minimally invasive clinically approved cancertreatment that was first applied in the early 20th century. PDT is an attractive alternative when compared to chemotherapy and radiation therapy due to the lack of harmfu...
Exploring the Immune System using Hybrid Cube Nanoparticles
Title
Exploring the Immune System using Hybrid Cube Nanoparticles
Author
McMillan, Jessica
Date Created
2021
Subjects--Topical
Biochemistry, Nanotechnology, Biology
Description
Nano-sized cubes made from nucleic acid material (NANPs) are ideal scaffolds for therapeutic nucleic acids (TNAs). Both utilize sequence specificity through base-pairing, providing controlled strand interaction, stability, and targeted targeting d...
ORGANIZATION OF BIOMOLECULES IN A 3-DIMENSIONAL SPACE
Title
ORGANIZATION OF BIOMOLECULES IN A 3-DIMENSIONAL SPACE
Author
Sajja, Sameer
Date Created
2019
Subjects--Topical
Nanotechnology, Biochemistry
Description
The human body operates using various stimuli-responsive mechanisms, dictating biological activity via reaction to external cues. Hydrogels are networked hydrophilic polymeric materials that offer the potential to recreate aqueous environments wit...
NUCLEIC ACID-DRIVEN QUANTUM DOT-BASED LATTICE FORMATIONS FOR BIOMEDICAL APPLICATIONS
Title
NUCLEIC ACID-DRIVEN QUANTUM DOT-BASED LATTICE FORMATIONS FOR BIOMEDICAL APPLICATIONS
Author
Roark, Brandon
Date Created
2017
Subjects--Topical
Nanoscience, Nanotechnology, Biochemistry
Description
We present a versatile biosensing strategy that uses nucleic acids programmed to undergo an isothermal toehold mediated strand displacement in the presence of analyte. This rearrangement results in a double biotinylated duplex formation that induc...
Thermal analysis of filler reinforced polymeric composites
Title
Thermal analysis of filler reinforced polymeric composites
Author
Ghadge, Mahesh
Date Created
2017
Subjects--Topical
Mechanics, Nanoscience, Nanotechnology
Description
Improving heat dissipating property of composite materials is becoming increasinglyimportant in domains ranging from the automotive industry, electronic devices toaeronautical industry. Effective heat dissipation is required especially in aircraft...