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Title: Elucidating Dynamic Mechanisms for Extended Spectrum Antibiotic Resistance in Class A Beta-Lactamase through Machine Learning on Molecular Dynamics Simulations
Author: Avery, Christopher
Date Created: 2019
Subjects--Topical: Biophysics, Physics
Description: Beta-lactamase is a protein which is produced in bacteria and is a primary cause of antibiotic resistance to Beta Lactam antibiotics. Beta Lactams are among the most common types of antibiotics (including penicillin) and thus understanding the res...

Title: THE SYNTHESIS OF PHOTOSENSITIZERS FOR THE PHOTODYNAMIC INACTIVATION OF ESCHERICHIA COLI
Author: Hurst, Alexandra
Date Created: 2017
Subjects--Topical: Chemistry
Description: The development of antibiotic resistance is a natural phenomenon that occurs when bacteria cells exchange resistant traits amongst each other or when mutations occur during replication. This causes bacteria to be able to withstand attack by antibi...

Title: The in-vivo Evolution of Burkholderia multivorans in a Cystic Fibrosis patient
Author: Harrison, Sarah
Date Created: 2021
Subjects--Topical: Biology, Microbiology, Bioinformatics
Description: ABSTRACT Burkholderia multivorans is an opportunistic pathogen that poses a health risk to patients with cystic fibrosis (CF). The use of broad-range antibiotics to combat chronic bacterial lung infections has led to the evolution of antibiotic-re...