Search results
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Title
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Modeling Plasmodium falciparum diagnostic test sensitivity using machine learning with histidine-rich protein 2 variants
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Author
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Ford, Colby, Janies, Daniel, Alemayehu, Gezahegn, Lo, Eugenia, Blackburn, Kayla, Lopez, Karen, Dieng, Cheikh Cambel, Golassa, Lemu
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Subjects--Topical
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Malaria, Plasmodium falciparum
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Description
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Malaria, predominantly caused by Plasmodium falciparum, poses one of largest and most durable health threats in the world. Previously, simplistic regression-based models have been created to characterize malaria rapid diagnostic test performance, ...
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Title
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Sequence-based identification of Anopheles species in eastern Ethiopia
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Author
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Janies, Daniel, Lopez, Karen
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Date Created
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2019
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background: The recent finding of a typically non-African Anopheles species in eastern Ethiopia emphasizes the need for detailed species identification and characterization for effective malaria vector surveillance. Molecular approaches increase t...
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Title
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Geographical distribution of Anopheles stephensi in eastern Ethiopia
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Author
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Janies, Daniel, Lopez, Karen
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Date Created
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2020
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background The recent detection of the South Asian malaria vector Anopheles stephensi in Ethiopia and other regions in the Horn of Africa has raised concerns about its potential impact on malaria transmission. We report here the findings of a surv...
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Title
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Insecticide resistance in Anopheles stephensi in Somali Region, eastern Ethiopia
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Author
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Janies, Daniel, Lopez, Karen
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Date Created
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2020
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background The movement of malaria vectors into new areas is a growing concern in the efforts to control malaria. The recent report of Anopheles stephensi in eastern Ethiopia has raised the necessity to understand the insecticide resistance status...
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Title
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Detection of high prevalence of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Assosa zone, Ethiopia : implication for malaria diagnosis
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Author
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Janies, Daniel, Blackburn, Kayla, Lopez, Karen, Lo, Eugenia
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Date Created
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2021
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background Rapid diagnostic tests (RDTs) targeting histidine rich protein 2(HRP2) are widely used for diagnosis of Plasmodium falciparum infections. Besides PfHRP2, the PfHRP3 antigen contributes to the detection of P. falciparum infections in PfH...
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Title
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Genetic diversity of Anopheles stephensi in Ethiopia provides insight into patterns of spread
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Author
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Janies, Daniel, Lopez, Karen
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Date Created
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2021
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background: The recent detection of the South Asian malaria vector Anopheles stephensi in the Horn of Africa (HOA) raises concerns about the impact of this mosquito on malaria transmission in the region. Analysis of An. stephensi genetic diversity...
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Title
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Genetic variation of Plasmodium falciparum histidine-rich protein 2 and 3 in Assosa zone, Ethiopia : its impact on the performance of malaria rapid diagnostic tests
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Author
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Janies, Daniel, Blackburn, Kayla, Lopez, Karen, Lo, Eugenia
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Date Created
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2021
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background Rapid diagnostic tests (RDT) are commonly used for the diagnosis of malaria caused by Plasmodium falciparum. However, false negative results of RDT caused by genetic variation of P. falciparum histidine-rich protein 2 and 3 genes (pfhrp...