Search results
-
-
Title
-
Submicroscopic infection and G6PD deficiency in malaria patients
-
Author
-
Witherspoon, Logan, Witherspoon, Logan, Kepple, Daniel, Lo, Eugenia, Abagero, Beka
-
Date Created
-
2022, 2022, 2022
-
Subjects--Topical
-
Malaria, Public health
-
Description
-
Plasmodium vivax malaria is a neglected tropical disease, despite being more geographically widespread than any other form of malaria. Glucose-6-phosphate dehydrogenase (G6PD) is a cytosolic enzyme with a vital role for the integrity and functioni...
-
-
Title
-
Modeling Plasmodium falciparum diagnostic test sensitivity using machine learning with histidine-rich protein 2 variants
-
Author
-
Ford, Colby, Janies, Daniel, Alemayehu, Gezahegn, Lo, Eugenia, Blackburn, Kayla, Lopez, Karen, Dieng, Cheikh Cambel, Golassa, Lemu
-
Subjects--Topical
-
Malaria, Plasmodium falciparum
-
Description
-
Malaria, predominantly caused by Plasmodium falciparum, poses one of largest and most durable health threats in the world. Previously, simplistic regression-based models have been created to characterize malaria rapid diagnostic test performance, ...
-
-
Title
-
Patch dynamics modeling framework from pathogens' perspective : Unified and standardized approach for complicated epidemic systems
-
Author
-
Janies, Daniel, Chen, Shi, Lo, Eugenia, Dulin, Michael
-
Date Created
-
2020
-
Subjects--Topical
-
Communicable diseases, Biology
-
Description
-
Mathematical models are powerful tools to investigate, simulate, and evaluate potential interventions for infectious diseases dynamics. Much effort has focused on the Susceptible-Infected-Recovered (SIR)-type compartment models. These models consi...
-
-
Title
-
Detection of high prevalence of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Assosa zone, Ethiopia : implication for malaria diagnosis
-
Author
-
Janies, Daniel, Blackburn, Kayla, Lopez, Karen, Lo, Eugenia
-
Date Created
-
2021
-
Subjects--Topical
-
Communicable diseases, Malaria
-
Description
-
Background Rapid diagnostic tests (RDTs) targeting histidine rich protein 2(HRP2) are widely used for diagnosis of Plasmodium falciparum infections. Besides PfHRP2, the PfHRP3 antigen contributes to the detection of P. falciparum infections in PfH...
-
-
Title
-
Genetic variation of Plasmodium falciparum histidine-rich protein 2 and 3 in Assosa zone, Ethiopia : its impact on the performance of malaria rapid diagnostic tests
-
Author
-
Janies, Daniel, Blackburn, Kayla, Lopez, Karen, Lo, Eugenia
-
Date Created
-
2021
-
Subjects--Topical
-
Communicable diseases, Malaria
-
Description
-
Background Rapid diagnostic tests (RDT) are commonly used for the diagnosis of malaria caused by Plasmodium falciparum. However, false negative results of RDT caused by genetic variation of P. falciparum histidine-rich protein 2 and 3 genes (pfhrp...
-
-
Title
-
Implementing landscape genetics in molecular epidemiology to determine drivers of vector‐borne disease : a malaria case study
-
Author
-
Lo, Eugenia, Janies, Daneil, Hubbard, Alfred, Afrane, Yaw
-
Date Created
-
2023
-
Subjects--Topical
-
Malaria, Protozoan diseases
-
Description
-
This study employs landscape genetics to investigate the environmental drivers of a deadly vector-borne disease, malaria caused by Plasmodium falciparum, in a more spatially comprehensive manner than any previous work. With 1804 samples from 44 si...