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Change in lipofectamine carrier as a tool to fine-tune immunostimulation of nucleic acid nanoparticles
Title
Change in lipofectamine carrier as a tool to fine-tune immunostimulation of nucleic acid nanoparticles
Author
Afonin, Kirill A., Newton, Hannah S., Xu, Jie
Date Created
2023
Subjects--Topical
Nucleic acids, Chemistry
Description
Nucleic acid nanoparticles (NANPs) require a carrier to allow for their intracellular delivery to immune cells. Cytokine production, specifically type I and III interferons, allows for reliable monitoring of the carrier effect on NANP immunostimul...