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Changes in Lysozyme flexibility upon mutation are frequent, large and long-ranged
Title
Changes in Lysozyme flexibility upon mutation are frequent, large and long-ranged
Author
Jacobs, Donald J., Verma, Deeptak, Livesay, Dennis R.
Date Created
2012
Subjects--Topical
Bioinformatics, Statistics
Description
We investigate changes in human c-type lysozyme flexibility upon mutation via a Distance Constraint Model, which gives a statistical mechanical treatment of network rigidity. Specifically, two dynamical metrics are tracked. Changes in flexibility ...
Analysis of pollen-specific alternative splicing in Arabidopsis thaliana via semi-quantitative PCR
Title
Analysis of pollen-specific alternative splicing in Arabidopsis thaliana via semi-quantitative PCR
Author
Loraine, Ann, Estrada, April, Freese, Nowlan H., Blakley, Ivory
Date Created
2015
Subjects--Topical
Bioinformatics, Pollen, Nucleic acids
Description
Alternative splicing enables a single gene to produce multiple mRNA isoforms by varying splice site selection. In animals, alternative splicing of mRNA isoforms between cell types is widespread and supports cellular differentiation. In plants, at ...
A new strategy to infer circularity applied to four new complete frog mitogenomes
Title
A new strategy to infer circularity applied to four new complete frog mitogenomes
Author
Machado, Denis Jacob, Janies, Daniel, Brouwer, Cory, Grant, Taran
Date Created
2018
Subjects--Topical
Genomics, Amphibians, Bioinformatics
Description
We applied a novel strategy to infer sequence circularity and complete assembly of four mitochondrial genomes (mitogenomes) of the frog families Bufonidae (Melanophryniscus moreirae), Dendrobatidae (Hyloxalus subpunctatus and Phyllobates terribili...
Arabidopsis bioinformatics resources : the current state, challenges, and priorities for the future
Title
Arabidopsis bioinformatics resources : the current state, challenges, and priorities for the future
Author
Loraine, Ann, Doherty, Colleen, Friesner, Joanna, Gregory, Brian
Date Created
2019
Subjects--Topical
Bioinformatics, Arabidopsis thaliana
Description
Effective research, education, and outreach efforts by the Arabidopsis thaliana community, as well as other scientific communities that depend on Arabidopsis resources, depend vitally on easily available and publicly-shared resources. These resour...
Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient
Title
Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient
Author
Loraine, Ann, Yao, Jianchao, Chang, Chunqi, Roux, Stanley J.
Date Created
2008
Subjects--Topical
Genomics, Bioinformatics
Description
Background: Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson correlation coefficient and the standard deviation (SD)-weighted correlat...