Search results
- Title
- ALGORITHMS FOR STRUCTURE BASED-PREDICTION OF TRANSCRIPTION FACTOR BINDING SITES
- Author
- Farrel, Alvin
- Date Created
- 2016
- Subjects--Topical
- Computer science, Biology, Bioinformatics
- Description
- Transcription factors (TFs) regulate gene expression through binding to specific target DNA sites. Accurate annotation of transcription factor binding sites (TFBSs) at genome scale represents an essential step toward our understanding of gene regu...
- Title
- Common Dietary and Environmental Compounds Promote a Leukemic Translocation in Hematopoietic Stem Cells and Differentiated Cells
- Author
- Vestal, Carol
- Date Created
- 2016
- Subjects--Topical
- Molecular biology, Biology, Genetics
- Description
- Maternal exposure to topoisomerase II (topoII) inhibitors that are biochemically similar to the chemotherapeutic drug etoposide may promote infant acute leukemia. Several studies have shown that common dietary bioflavonoids as well as benzene meta...
- Title
- Comparative analysis of Nitrosococcus genomes; isolation, physiological and genomic characterization of the new ammonia-oxidizing species Nitrosococcus wardiae, strain D1FHST; and molecular studies towards a better understanding of ammonia-dependent chemolithotrophy
- Author
- Wang, Lin
- Date Created
- 2016
- Subjects--Topical
- Molecular biology, Biology, Genetics
- Description
- Obligate aerobic chemolithoautotrophic ammonia-oxidzing bacteria (AOB) derive energy and reductant needed for growth solely from the oxidation of ammonia to nitrite thereby facilitating the process of nitritation. A strain of an ammonia-oxidizing ...
- Title
- Daily cycle in oxygen consumption by the sea anemone Nematostella vectensis Stephenson
- Author
- Reitzel, Adam M., Maas, Amy E., Jones, Ian T.
- Date Created
- 2016
- Subjects--Topical
- Gene expression, Biology
- Description
- In bilaterian animals, the circadian clock is intimately involved in regulating energetic metabolism. Although cnidarians exhibit diel behavioral rhythms including cycles in locomotor activity, tentacle extension and spawning, daily cycles in cnid...
- Title
- Developmental expression of germline- and sex determination-related genes in the ctenophore Mnemiopsis leidyi
- Author
- Reitzel, Adam M., Pang, Kevin, Martindale, Mark Q.
- Date Created
- 2016
- Subjects--Topical
- Evolution (Biology), Biology
- Description
- Background: An essential developmental pathway in sexually reproducing animals is the specification of germ cells and the differentiation of mature gametes, sperm and oocytes. The germline genes vasa, nanos and piwi are commonly identified in prim...
- Title
- ELUCIDATING THE MOLECULAR BASIS OF INHIBITION OF ENZYMES ESSENTIAL FOR BATERIALVIRULENCE: THE ACTIVITY OF THREE GLYCOSYLTRANSFERASES AND A POTENTIAL DRUG TARGET, UNDECAPRENYL PYROPHOSPHATE SYNTHASE
- Author
- Okwei, Elleansar
- Date Created
- 2016
- Subjects--Topical
- Chemistry, Biology, Biochemistry
- Description
- The fight against bacterial infection is one of the most important branches of modern medicine. Due to the emergence of strains of antibiotic-resistant bacteria, researchers have been presented with complex challenges in an effort to combat these ...
- Title
- EchinoDB, an application for comparative transcriptomics of deeply-sampled clades of echinoderms
- Author
- Janies, Daniel, Witter, Zachary, Linchangco, Gregorio V., Jr.
- Date Created
- 2016
- Subjects--Topical
- Genomics, Biology
- Description
- Background: One of our goals for the echinoderm tree of life project (http://echinotol.org) is to identify orthologs suitable for phylogenetic analysis from next-generation transcriptome data. The current dataset is the largest assembled for echin...
- Title
- THE ROLE OF TRANSLESION SYNTHESIS POLYMERASES REV1 AND POL η IN DNA DAMAGE RESPONSE
- Author
- McLeod, Melissa
- Date Created
- 2016
- Subjects--Topical
- Molecular biology, Biology, Cytology
- Description
- Our cells endure continuous challenges from byproducts of endogenous metabolic processes as well as outside sources such as UV light and environmental polltants. The DNA Damage Response (DDR) helps organisms cope with damage and coordinate an appr...
- Title
- The Moon Jellyfish (Aurelia aurita): A Prospective Pelagic and Estuarine Bioindicator
- Author
- Lowder, Matthew
- Date Created
- 2016
- Subjects--Topical
- Biology, Environmental sciences, Toxicology
- Description
- Due in part to the complexity of scyphozoan life histories, slight changes in environmental factors can have an effect on fecundity, growth & development and population fluctuations. Anthropogenic activities have been suggested as a major cause of...
- Title
- Towards The Dry Preservation of Feline Sperm: The Effect Of Dehydration On DNA, Centrosomal Function, And Embryo Development
- Author
- Patrick, Jennifer
- Date Created
- 2016
- Subjects--Topical
- Biology
- Description
- The current gold standard for gamete preservation is cryogenic storage. Dry preservation is an attractive alternative, eliminating the need for refrigeration, reducing storage maintenance costs, and providing logistical flexibility for shipping. T...
- Title
- Using Nematostella vectensis to study the interactions between genome, epigenome, and bacteria in a changing environment
- Author
- Reitzel, Adam M., Fraune, Sebastian, Foret, Sylvain
- Date Created
- 2016
- Subjects--Topical
- Gene expression, Biology
- Description
- The phenotype of an animal cannot be explained entirely by its genes. It is now clear that factors other than the genome contribute to the ecology and evolution of animals. Two fundamentally important factors are the associated microbiota and epig...
- Title
- Variation in Patterns of Allocare In Captive Hamadryas Baboons (Papio hamadryas): The Potential Effects of Environment and Kinship in the Development of Novel Behavior
- Author
- Carter, Amanda
- Date Created
- 2016
- Subjects--Topical
- Biology, Physical anthropology, Zoology
- Description
- The goal of the this research was to examine the social dynamics among extended matrilines of Hamadryas baboons (Papio hamadryas) housed at the North Carolina Zoo (NCZ) in Asheboro, North Carolina, including the putative existence of allocare, def...