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ALGORITHMS FOR STRUCTURE BASED-PREDICTION OF TRANSCRIPTION FACTOR BINDING SITES
Title
ALGORITHMS FOR STRUCTURE BASED-PREDICTION OF TRANSCRIPTION FACTOR BINDING SITES
Author
Farrel, Alvin
Date Created
2016
Subjects--Topical
Computer science, Biology, Bioinformatics
Description
Transcription factors (TFs) regulate gene expression through binding to specific target DNA sites. Accurate annotation of transcription factor binding sites (TFBSs) at genome scale represents an essential step toward our understanding of gene regu...
CHARACTERIZING NEXT-GENERATION SEQUENCING (NGS) PLATFORMS FOR MULTIPLEXED BIOSENSING AND APTAMER DISCOVERY: G-QUADRUPLEX APTAMERS AS A CASE STUDY
Title
CHARACTERIZING NEXT-GENERATION SEQUENCING (NGS) PLATFORMS FOR MULTIPLEXED BIOSENSING AND APTAMER DISCOVERY: G-QUADRUPLEX APTAMERS AS A CASE STUDY
Author
Patil, Sushant
Date Created
2016
Subjects--Topical
Molecular biology, Bioinformatics, Biochemistry
Description
Aptamers are single-stranded DNA or RNA molecules forming unique three dimensional structures that can bind to their targets (generally proteins or metabolites or other nucleic acids) with high specificity and affinity. Screening for aptamers requ...
Next-Generation Sequencing Based Quantification of Microbial Communities and Gene Pathways
Title
Next-Generation Sequencing Based Quantification of Microbial Communities and Gene Pathways
Author
Jones, Roshonda
Date Created
2016
Subjects--Topical
Bioinformatics
Description
Humans act as a host to trillions of microorganisms. The collective of these microorganisms is called a host’s microbiota. There is a growing interest in the bacterial composition of the gut microbiome of humans (structure) and the role of the mic...
Structural analysis of protein-DNA binding specificity and its application to protein-DNA docking assessment
Title
Structural analysis of protein-DNA binding specificity and its application to protein-DNA docking assessment
Author
Corona de la Fuente, Rosario
Date Created
2016
Subjects--Topical
Bioinformatics
Description
DNA-binding proteins are involved in essential biological processes including gene expression, DNA packaging and DNA repair. They bind to DNA target sequences with different degrees of binding specificity, ranging from highly specific to non-speci...
The evolution of flavonoid pathway in legumes
Title
The evolution of flavonoid pathway in legumes
Author
Safari, Sajedeh
Date Created
2016
Subjects--Topical
Bioinformatics
Description
Considering the ever growing world population as well as climate change, it has become essential to improve crops in order to reach higher yields, more tolerance to pests and droughts, and better adaptation to different environments. The advanceme...
UNDERSTANDING GENOME-WIDE GENE REGULATION IN PROKARYOTES USING OMICS DATA
Title
UNDERSTANDING GENOME-WIDE GENE REGULATION IN PROKARYOTES USING OMICS DATA
Author
Seyedi Tabari, Seyed Ehsan
Date Created
2016
Subjects--Topical
Bioinformatics, Information science, Biometry
Description
Gene annotation is a critical step for understanding functions of genomes and host organisms. However, accurately annotating thousands of sequenced genomes can be a challenging task. Further, although gene transcriptional regulation is crucial for...