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Low-dose metformin treatment reduces in vitro growth of the LL/2 non-small cell lung cancer cell line
Title
Low-dose metformin treatment reduces in vitro growth of the LL/2 non-small cell lung cancer cell line
Author
Marino, Joseph S., Dreau, Didier, Marriott, Ian, Bennett, Jeanette M.
Date Created
2022
Subjects--Topical
Cancer cells, Lungs--Cancer
Description
Lung cancer maintains a relatively small survival rate (~19%) over a 5-year period and up to 80-85% of all lung cancer diagnoses are Non-Small Cell Lung Cancer (NSCLC). To determine whether metformin reduces non-small cell lung cancer (NSCLC) LL/2...
A new obligate CXCL4-CXCL12 heterodimer for studying chemokine heterodimer activities and mechanisms
Title
A new obligate CXCL4-CXCL12 heterodimer for studying chemokine heterodimer activities and mechanisms
Author
Nesmelova, Irina, Ngyuen, Khanh T.P., Dreau, Didier, Volkman, Brian
Date Created
2022
Subjects--Topical
Chemokines, Proteins
Description
Chemokines form a family of proteins with critical roles in many biological processes in health and disease conditions, including cardiovascular, autoimmune diseases, infections, and cancer. Many chemokines engage in heterophilic interactions to f...