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Examining the Contribution of the DNA Damage Response to Sepsis Survivor Myelosuppression
Title
Examining the Contribution of the DNA Damage Response to Sepsis Survivor Myelosuppression
Author
Huff, Laura
Date Created
2020
Subjects--Topical
Immunology, Biology, Pathology
Description
A large portion of patients who survive sepsis, a life-threatening hyperinflammatory response to infection resulting in organ dysfunction, experience a higher risk of mortality than non-septic patients. Innate immune cells of sepsis survivors exhi...
ROLE OF THE NOVEL DNA SENSORS cGAS, IFI16, AND ZBP1, DURING VIRAL INFECTIONS IN GLIA
Title
ROLE OF THE NOVEL DNA SENSORS cGAS, IFI16, AND ZBP1, DURING VIRAL INFECTIONS IN GLIA
Author
Jeffries, Austin
Date Created
2020
Subjects--Topical
Immunology, Virology, Neurosciences
Description
Viral central nervous system (CNS) infections can lead to life threatening encephalitis and long-term neurological deficits in survivors. Resident CNS cell types, such as astrocytes and microglia, are known to produce key inflammatory and antivira...