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ComparePD : improving protein–DNA complex model comparison with hydrogen bond energy-based metrics
Title
ComparePD : improving protein–DNA complex model comparison with hydrogen bond energy-based metrics
Author
Guo, Jun-tao, Malik, Fareeha Kanwal
Date Created
2023
Subjects--Topical
DNA, Nucleic acids
Description
Computational modeling of protein–DNA complex structures has important implications in biomedical applications such as structure-based, computer aided drug design. A key step in developing methods for accurate modeling of protein–DNA complexes is ...
Modeling of ssDNA binding protein structures
Title
Modeling of ssDNA binding protein structures
Author
Jariwala, Maanav, Guo, Jun-tao
Date Created
2022
Subjects--Topical
DNA, Protein binding
Description
Single-stranded DNA (ssDNA) binding proteins are crucial for biological processes including replication, transcription, and genomic integrity. We can better comprehend the function of the proteins and their interactions with ssDNA with structures ...
PROTEIN-PROTEIN INTERACTION OF PAI-H19Y MUTANT OF THE SLEEPING BEAUTY TRANSPOSASE
Title
PROTEIN-PROTEIN INTERACTION OF PAI-H19Y MUTANT OF THE SLEEPING BEAUTY TRANSPOSASE
Author
Yan, Chenbo
Date Created
2020
Subjects--Topical
Biophysics, DNA
Description
Due to the substantial interest in developing transposon technology for gene delivery and gene therapy, the Sleeping Beauty (SB) transposon system, the most active transposon in the vertebrate species, has been extensively studied. The SB transpos...