Search results | J. Murrey Atkins Library

Title: Analysis and Development of Targeting Strategies for Bacterial Sugars
Author: Erickson, Katelyn
Date Created: 2018
Subjects--Topical: Chemistry, Biochemistry
Description: Bacterial cell surface exopolysaccharides aid in protecting microbes from the defense mechanisms of the host, and differ substantially in structure between species. Exploiting these structural differences would be advantageous to target certain ty...

Title: Artificial immune cell, AI-cell, a new tool to predict interferon production by peripheral blood monocytes in response to nucleic acid nanoparticles
Author: Afonin, Kirill A., Chandler, Morgan, Halman, Justin
Date Created: 2022
Subjects--Topical: Nucleic acids, Chemistry
Description: Nucleic acid nanoparticles, or NANPs, rationally designed to communicate with the human immune system, can offer innovative therapeutic strategies to overcome the limitations of traditional nucleic acid therapies. Each set of NANPs is unique in th...

Title: Biomotors, viral assembly, and rna nanobiotechnology: current achievements and future directions
Author: Afonin, Kirill A., Rolband, Lewis
Date Created: 2022
Subjects--Topical: Nucleic acids, Chemistry
Description: The International Society of RNA Nanotechnology and Nanomedicine (ISRNN) serves to further the development of a wide variety of functional nucleic acids and other related nanotechnology platforms. To aid in the dissemination of the most recent adv...

Title: Broccoli fluorets : split aptamers as a user-friendly fluorescent toolkit for dynamic RNA nanotechnology
Author: Afonin, Kirill A., Chandler, Morgan, Halman, Justin
Date Created: 2018
Subjects--Topical: Nucleic acids, Chemistry
Description: RNA aptamers selected to bind fluorophores and activate their fluorescence offer a simple and modular way to visualize native RNAs in cells. Split aptamers which are inactive until the halves are brought within close proximity can become useful fo...

Title: Change in lipofectamine carrier as a tool to fine-tune immunostimulation of nucleic acid nanoparticles
Author: Afonin, Kirill A., Newton, Hannah S., Xu, Jie
Date Created: 2023
Subjects--Topical: Nucleic acids, Chemistry
Description: Nucleic acid nanoparticles (NANPs) require a carrier to allow for their intracellular delivery to immune cells. Cytokine production, specifically type I and III interferons, allows for reliable monitoring of the carrier effect on NANP immunostimul...

Title: Characterization of cationic bolaamphiphile vesicles for sirna delivery into tumors and brain
Author: Afonin, Kirill A., Kim, Taejin, Gupta, Kshitij
Date Created: 2020
Subjects--Topical: Nucleic acids, Chemistry
Description: Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug Administration (FDA) of the first siRNA therapeutic agent (patisiran). Howeve...

Title: Crystalline Silicon Interfaces with Adhesive Polymer Semiconducting Glue and Thiazolothiazole Redox Active Organic Small Molecules
Author: Cohen, Daniel
Date Created: 2020
Subjects--Topical: Materials science, Chemistry, Chemistry, Organic
Description: Crystalline silicon is an extremely versatile semiconductor material used for electronics and photovoltaic devices. An organic conductive glue based on a blend of poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) and d-sorbitol ...

Title: DNA-templated fluorescent silver nanoclusters inhibit bacterial growth while being non-toxic to mammalian cells
Author: Afonin, Kirill A., Chandler, Morgan, Rolband, Lewis
Date Created: 2021
Subjects--Topical: Nucleic acids, Chemistry
Description: Silver has a long history of antibacterial effectiveness. The combination of atomically precise metal nanoclusters with the field of nucleic acid nanotechnology has given rise to DNA-templated silver nanoclusters (DNA-AgNCs) which can be engineere...

Title: Design and Modulation of Novel Chemical Probes for RNA SHAPE Analysis: Water Soluble Isatoic Anhydrides and Nicotinic Acid Imidazolides
Author: Fessler, Adam
Date Created: 2021
Subjects--Topical: Chemistry, Biology
Description: The growing interest in RNA biology, along with an expansion in computational capabilities, throughput, and sensitivity has provided researchers new tools to probe RNA. RNA selective 2′-hydroxy acylation analyzed by primer extension (SHAPE) utiliz...

Title: Development of nanoparticle-based approaches for the treatment and imaging of pancreatic cancer
Author: Tarannum, Mubin
Date Created: 2020
Subjects--Topical: Nanoscience, Chemistry
Description: Pancreatic ductal adenocarcinoma (PDAC) is a type of exocrine pancreatic cancer which accounts for over 90% of cases. PDAC is the fourth-leading cause of cancer-related mortality in the United States with a 5-year survival rate of 9% with little t...

Title: Editorial for the special issue on nucleic acid architectures for therapeutics, diagnostics, devices and materials
Author: Afonin, Kirill A., Halman, Justin
Date Created: 2019
Subjects--Topical: Nucleic acids, Chemistry

Title: Electrochromic, Electrofluorochromic, and Photoactive Properties of Thiazolothiazole-Based, Multifunctional Materials
Author: Adams, Tyler
Date Created: 2023
Subjects--Topical: Chemistry, Nanoscience
Description: There have been an increasing number of materials developed that show multifunctional chromogenic properties (such as electrochromism, electrofluorochromism, or photochromism), but to date, few materials have shown all three properties. Materials ...

Title: Exosome mediated delivery of functional nucleic acid nanoparticles (NANPs)
Author: Afonin, Kirill A., Ke, Weina
Date Created: 2020
Subjects--Topical: Nucleic acids, Chemistry
Description: RNAi-based technologies have shown biomedical potential; however, safe and efficient delivery of RNA remains a barrier for their broader clinical applications. Nucleic acid nanoparticles (NANPs) programmed to self-assemble and organize multiple th...

Title: Expanding structural space for immunomodulatory nucleic acid nanoparticles (NANPs) via spatial arrangement of their therapeutic moieties
Author: Afonin, Kirill A., Chandler, Morgan, Rolband, Lewis
Date Created: 2022
Subjects--Topical: Nucleic acids, Chemistry
Description: Different therapeutic nucleic acids (TNAs) can be unified in a single structure by their elongation with short oligonucleotides designed to self-assemble into nucleic acid nanoparticles (NANPs). With this approach, therapeutic cocktails with preci...

Title: Exploring the photophysics and photocatalytic properties of platinum and palladium nanoparticles
Author: Major, Kevin
Date Created: 2012
Subjects--Topical: Nanoscience, Chemistry, Chemistry, Physical and theoretical
Description: Platinum and Palladium nanoparticles are important nanoscale materials for a variety of materials science and industrial applications. The presented research covers a broad spectrum of these unique nanoparticles, from their synthesis and character...

Title: First step towards larger DNA-based assemblies of fluorescent silver nanoclusters: template design and detailed characterization of optical properties
Author: Afonin, Kirill A., Shevchenko, Oleg
Date Created: 2019
Subjects--Topical: Nucleic acids, Chemistry
Description: Besides being a passive carrier of genetic information, DNA can also serve as an architecture template for the synthesis of novel fluorescent nanomaterials that are arranged in a highly organized network of functional entities such as fluorescent ...

Title: Functionally-interdependent shape-switching nanoparticles with controllable properties
Author: Afonin, Kirill A., Halman, Justin, Chandler, Morgan
Date Created: 2017
Subjects--Topical: Nucleic acids, Chemistry
Description: We introduce a new concept that utilizes cognate nucleic acid nanoparticles which are fully complementary and functionally-interdependent to each other. In the described approach, the physical interaction between sets of designed nanoparticles ini...

Title: Hexacoordinate Silicon Complexes as Cathodic Colorants
Author: Peloquin, Derek
Date Created: 2016
Subjects--Topical: Nanoscience, Chemistry, Chemistry, Inorganic
Description: Electrochemical and spectroelectrochemical characterization of hexacoordinate polypyridine silicon complexes show that they are fitting candidates for electrochromic applications. Tris(bipyridine)silicon(IV), [Si(bpy)3]+4, is colorless in acetonit...

Title: Induction of cytokines by nucleic acid nanoparticles (NANPs) depends on the type of delivery carrier
Author: Afonin, Kirill A., Chandler, Morgan, Avila, Yelixza I.
Date Created: 2021
Subjects--Topical: Nucleic acids, Chemistry
Description: Recent insights into the immunostimulatory properties of nucleic acid nanoparticles (NANPs) have demonstrated that variations in the shape, size, and composition lead to distinct patterns in their immunostimulatory properties. While most of these ...

Title: LOADED AND ELABORATED POLYESTER NANOMATERIALS FOR THE TREATMENT AND DIAGNOSIS OF DISEASE
Author: Fowler, Anthony
Date Created: 2017
Subjects--Topical: Chemistry, Nanotechnology
Description: Cancer is not one disease but many. In fact, cancer is a collection of more than 100 different diseases. Cancer is the second leading cause of death in the United States with an estimated 1.7 million new cases expected in 2017 and approximately 60...